Massachusetts Eye and Ear Infirmary

Boston, Massachusetts 02127

14 studies enrolling now · 112 studies all time

What they study most

AMD, Achromatopsia, Adenoidectomy, Adenoviral Conjunctivitis, Age-related Macular Degeneration, Age-related Macular Degeneration (AMD), Amblyopia, Anterior Uveitis, Autoimmune Diseases, Bacterial Conjunctivitis, Bilateral Hearing Loss for Causes Other Than Tumors, Bilateral Sensorineural Hearing Loss

Studies at this site

• A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy — Recruiting now
• A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease — Recruiting now
• Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD — Recruiting now
• Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia — Recruiting now
• Imaging Genetics of Laryngeal Dystonia — Recruiting now
• An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus — Recruiting now
• Brain-Computer Interfaces in Laryngeal Dystonia — Recruiting now
• Efgartigimod for the Treatment of Acute Optic Neuritis — Recruiting now
• Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy — Recruiting now
• An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene — Recruiting now
• A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1) — Recruiting now
• Study of Remimazolam for Cataract Surgery — Starting soon
• Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene — Running, not enrolling
• A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP) — Running, not enrolling
• Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease — Completed
• A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD) — Completed
• A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma — Running, not enrolling
• Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery — Enrolling by invitation
• Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year — Completed
• A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients — Starting soon
• REALITY LHON Registry — Completed
• Assessment of Corneal Endothelial Function Following Hypoxic Stress — Withdrawn before enrolling
• Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2) — Completed
• Long-term Follow-up Gene Therapy Study for RPGR- XLRP — Completed
• A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC — Running, not enrolling
• Extension Study of NT-501 Ciliary Neurotrophic Factor (CNTF) Implant for Macular Telangiectasia (MacTel) — Completed
• Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma — Withdrawn before enrolling
• Zoster Eye Disease Study — Completed
• Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma — Completed
• Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft — Completed
• Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis — Completed
• The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea — Status unconfirmed
• 4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular Migraine — Withdrawn before enrolling
• Vestibular Implants Tested in Human Subjects — Withdrawn before enrolling
• Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR) — Completed
• Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty — Completed
• Retinoblastoma Biomarker Study — Completed
• Study in Subjects With Small Primary Choroidal Melanoma — Completed
• Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations — Completed
• Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial — Completed
• Safety and Tolerability of hRPC in Retinitis Pigmentosa — Status unconfirmed
• Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS) — Completed
• Vestibular Precision: Physiology & Pathophysiology — Status unconfirmed
• Single Ascending Dose Study in Participants With LCA10 — Status unconfirmed
• Allogeneic ABCB5-positive Limbal Stem Cells for Treatment of LSCD — Status unconfirmed
• A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer — Completed
• A Study to Test the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human Cornea — Completed
• Safety and Efficacy Trial of AAV Gene Therapy in Patients With CNGB3 Achromatopsia (A Clarity Clinical Trial) — Status unconfirmed
• Safety and Efficacy Trial of AAV Gene Therapy in Patients With CNGA3 Achromatopsia (A Clarity Clinical Trial) — Running, not enrolling
• Dry Eye Assessment and Management Study — Completed