Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR)
Completed
Conditions studied: Retinitis Pigmentosa
In brief
The rod-cone dystrophies (often referred to as retinitis pigmentosa (RP)) are a clinically and genetically heterogeneous group of disorders in which there is progressive loss of rod and later cone photoreceptor function leading to severe visual impairment. RP usually occurs as an isolated retinal disorder, but it may also be seen in association with systemic abnormalities.
Key facts
- Study ID
- NCT03349242
- Run by
- MeiraGTx UK II Ltd
- People needed
- 140
- Starts
- 2017-12-19
- Expected to finish
- 2024-04-19
- Last updated by the study team
- 2024-06-20
Who can join
Age: 5 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Males \& Females aged 5 years or older
- Have RPGR-associated retinal dystrophy
- Are able to give informed consent or assent, with the guidance of their parent/guardian where appropriate
- Are able to undertake age-appropriate clinical assessments as specified in the protocol
- Have genetic mutation within the RPGR gene confirmed by an accredited lab or research lab.
You may not qualify if…
- Are unable or unwilling to undertake consent or clinical testing
Where it is running
- Shiley Eye Institute - UCSD — La Jolla, California, United States
- Stanford University, Spencer Center for Vision Research — Stanford, California, United States
- Emory Eye Centre — Atlanta, Georgia, United States
- Massachusetts Eye and Ear Infirmary — Boston, Massachusetts, United States
- Kellogg Eye Center — Ann Arbor, Michigan, United States
- UPMC Eye Centre — Pittsburgh, Pennsylvania, United States
- The Hospital for Sick Children — Toronto, Canada
- Moorfields Eye Hospital — London, United Kingdom
Full record on ClinicalTrials.gov
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