Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty

Completed · Early Phase 1

Conditions studied: Fuchs' Endothelial Dystrophy

In brief

This will be a prospective assessment of whether adjuvant Netarsudil use in patients undergoing Descemetorhexis without endothelial keratoplasty improves time to corneal clearance and post-operative central endothelial cell counts. The anticipated enrollment is 25 patients.

Key facts

Study ID

NCT04752020

Run by

Massachusetts Eye and Ear Infirmary

People needed

25

Starts

2021-03-28

Expected to finish

2023-12-30

Last updated by the study team

2024-03-13

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Fuchs corneal dystrophy

You may not qualify if…

• Women of childbearing potential
• Other corneal eye diseases
• Non-compliance with netarsudil
• Intolerance of netarsudil

Where it is running

• Massachusetts Eye and Ear Infirmary — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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