A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma

Running, not enrolling

Conditions studied: Choroidal Melanoma, Indeterminate Lesions of Eye

In brief

The purpose of this observational research study is to follow participants who have been treated with bel-sar while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. The study will collect information based on assessments performed as part of the standard of care (SoC) for subjects with IL/CM, inclusive of all adverse events, concomitant medications and/or procedures, information regarding metastatic disease and details of treatments administered, and information about melanoma-related and all-cause mortality and cause of death (if applicable).

Key facts

Study ID

NCT03941379

Run by

Aura Biosciences

People needed

63

Starts

2019-03-27

Expected to finish

2029-12-01

Last updated by the study team

2026-05-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have been clinically diagnosed with primary IL or CM at the time of entry to a previous Aura Biosciences sponsored clinical trial.
• Have received AU-011 bel-sar treatment in a previous Aura Biosciences sponsored clinical trial.
• Have completed the exit visit of the previous Aura Biosciences sponsored clinical trial within 1 year of Day 1 (≤365 days) of enrollment into the Registry.

You may not qualify if…

• None

Where it is running

• Retina Associates SW, P.C. — Tucson, Arizona, United States
• UCLA Jules Stein Eye Institute — Los Angeles, California, United States
• Byers Eye Institute at Stanford University — Palo Alto, California, United States
• Retina Consultants of Sacramento — Sacramento, California, United States
• Massachusetts Eye and Ear Infirmary — Boston, Massachusetts, United States
• W. K. Kellogg Eye Center, University of Michigan — Ann Arbor, Michigan, United States
• Associated Retinal Consultants, PC — Royal Oak, Michigan, United States
• Retina Center — Minneapolis, Minnesota, United States
• Columbia University Medical Center — New York, New York, United States
• Oregon Health & Science University Casey Eye Institute — Portland, Oregon, United States
• Wills Eye Hospital — Philadelphia, Pennsylvania, United States
• Retina Consultants of Carolina, PA — Greenville, South Carolina, United States
• St. Thomas Health / Tennessee Retina, PC — Nashville, Tennessee, United States
• Texas Retina Associates — Dallas, Texas, United States
• Retina Consultants of Houston — Houston, Texas, United States
• University of Wisconsin — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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