University Health Network/Toronto General Hospital

Toronto, Ontario MSG 2C4

4 studies enrolling now · 51 studies all time

What they study most

ARDS, Anemia, Sickle Cell, Arterial Thrombosis, Bronchiolitis Obliterans Syndrome, COVID-19, Cancer, Candidemia, Candidiasis, Invasive, Carcinoma, Cardiovascular Diseases, Chronic Kidney Disease, Chronic Thromboembolic Pulmonary Hypertension

Studies at this site

• EXtubation Related Complications - the EXTUBE Study (EXTUBE) — Recruiting now
• Trifecta-Lung cfDNA-MMDx Study — Recruiting now
• A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia — Recruiting now
• Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation — Recruiting now
• To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva — Recruiting now
• MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) — Recruiting now
• A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole — Stopped early
• Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension — Running, not enrolling
• A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients — Completed
• A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS) — Running, not enrolling
• A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent Thalassemia — Running, not enrolling
• 10°C vs 4°C Lung Preservation RCT — Running, not enrolling
• A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension — Enrolling by invitation
• A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC) — Running, not enrolling
• A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer — Running, not enrolling
• A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease — Completed
• Safety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung Transplantation — Stopped early
• A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension — Stopped early
• A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (Core OLE) — Completed
• Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease — Completed
• PeriOperative ISchemic Evaluation-3 Trial — Completed
• Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections — Completed
• Evaluation of Dalteparin for Long-term (One Year) Treatment of Blood Clots in Subjects With Cancer — Completed
• A Study of RVT-1401 in Myasthenia Gravis (MG) Patients — Completed
• Effect of Tiotropium (Spiriva) on Exercise Tolerance in COPD Patients — Completed
• Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen — Completed
• Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis — Stopped early
• Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH) — Completed
• Awake Prone Position in Hypoxemic Patients With Coronavirus Disease 19 COVID-19 (COVI-PRONE) — Completed
• Open-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS) — Completed
• Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects — Completed
• Study to Evaluate Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Positive Participants — Completed
• Ultra-Low Tidal Volume Mechanical Ventilation in ARDS Through ECMO — Status unconfirmed
• Development of an Evidenced-Based Tool for Prediction of Sudden Death in Patients With Non-Ischemic Cardiomyopathy — Completed
• Switch Study to Evaluate F/TAF in HIV-1 Positive Participants Who Are Virologically Suppressed on Regimens Containing FTC/TDF — Completed
• A Study of Vonapanitase (PRT-201) Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-2) — Completed
• Efficacy and Safety of E/C/F/TAF (Genvoya®) in HIV-1/Hepatitis B Co-infected Adults — Completed
• Transfusion Requirements in Cardiac Surgery III — Completed
• Early Diagnosis of Pulmonary Nodules — Completed
• Multicenter, Randomized, Double-Blind, Double-Dummy, Phase 3 Study of the Safety and Efficacy of Elvitegravir Versus Raltegravir — Completed
• Safety and Efficacy of COBI-boosted Atazanavir Versus Ritonavir-boosted Atazanavir Each Administered With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults — Completed
• Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1 — Stopped early
• Study to Evaluate the Safety and Efficacy of Stribild Versus Ritonavir-Boosted Atazanavir Plus Truvada in Human Immunodeficiency Virus, Type 1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults — Completed
• Assessment of Pain in People With Thalassemia Who Are Treated With Regular Blood Transfusions — Completed
• Effects of HQK-1001 in Patients With Sickle Cell Disease — Stopped early
• Study to Evaluate the Safety and Efficacy of a Single Tablet Regimen of Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate Compared With a Single Tablet Regimen of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults — Completed
• The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome — Completed
• A Study of HQK-1001 in Patients With Sickle Cell Disease — Completed
• Biomarker Sub Study of the Compression Stockings to Prevent the Post-Thrombotic Syndrome (SOX) Trial — Completed
• SR34006 Compared to Vitamin K Antagonist (VKA) in the Treatment of Pulmonary Embolism — Completed