Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen

Completed · Phase 3 · Has a placebo group

Conditions studied: HBeAg-positive Chronic Hepatitis B

In brief

The primary objective of this study is to compare the efficacy, safety, and tolerability of tenofovir alafenamide (TAF) versus tenofovir disoproxil fumarate (TDF) in treatment-naive and treatment-experienced adults with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B virus (HBV) infection.

Key facts

Study ID
NCT01940471
Run by
Gilead Sciences
People needed
875
Starts
2013-09-11
Expected to finish
2022-10-13
Last updated by the study team
2023-10-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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