Biomarker Sub Study of the Compression Stockings to Prevent the Post-Thrombotic Syndrome (SOX) Trial

Completed

Conditions studied: Deep Venous Thrombosis

In brief

The purpose of this study is to evaluate whether biomarkers of inflammation, genetic thrombophilia and coagulation activation influence Post-Thrombotic Syndrome development in patients with symptomatic proximal deep venous thrombosis.

Key facts

Study ID

NCT01615705

Run by

Sir Mortimer B. Davis - Jewish General Hospital

People needed

803

Starts

2004-06-01

Expected to finish

2012-02-01

Last updated by the study team

2012-06-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Consecutive patients with a first, symptomatic, objectively confirmed proximal DVT diagnosed within the last 14 days (with or without concurrent distal DVT or pulmonary embolism)
• Who have no contraindications to standard treatment with heparin and/or warfarin, and
• Who provide informed consent to participate

You may not qualify if…

• Contraindication to compression stockings Limited lifespan (estimated < 6 months)
• Geographic inaccessibility preventing return for follow-up visits
• Inability to apply stockings daily and unavailability of a caregiver to apply stockings daily
• Treatment of acute DVT with thrombolytic agents

Where it is running

• Henry Ford Health System — Detroit, Michigan, United States
• Duke University Medical Center — Durham, North Carolina, United States
• Oklahoma University Health Sciences Center — Oklahoma City, Oklahoma, United States
• Victoria Heart Institute Foundation — Victoria, British Columbia, Canada
• St. Boniface General Hospital — Winnipeg, Manitoba, Canada
• QE II Health Sciences Centre — Halifax, Nova Scotia, Canada
• Hamilton Health Sciences - General Hospital — Hamilton, Ontario, Canada
• Hamilton Health Sciences - Chedoke Division — Hamilton, Ontario, Canada
• Hamilton Health Sciences - McMaster University Medical Centre — Hamilton, Ontario, Canada
• St. Joseph's Healthcare Hamilton — Hamilton, Ontario, Canada
• Hamilton Health Sciences - Henderson General Hospital — Hamilton, Ontario, Canada
• London Health Sciences Centre — London, Ontario, Canada
• The Ottawa Hospital, Civic Campus — Ottawa, Ontario, Canada
• Sunnybrook & Women's College Health Sciences Centre — Toronto, Ontario, Canada
• University Health Network - Toronto General Hospital — Toronto, Ontario, Canada
• Centre Hospitalier Pierre-Boucher — Longueuil, Quebec, Canada
• Hôpital Maisonneuve-Rosemont — Montreal, Quebec, Canada
• Centre Hospitalier de l'Université de Montréal - Hôpital Notre Dame — Montreal, Quebec, Canada
• Montreal General Hospital - McGill University Health Centre — Montreal, Quebec, Canada
• Sir Mortimer B. Davis -Jewish General Hospital — Montreal, Quebec, Canada
• St. Mary's Hospital Center — Montreal, Quebec, Canada
• Hôpital du Sacré-Coeur de Montréal — Montreal, Quebec, Canada
• Centre Hospitalier de l'Université de Montréal - Hôpital Hôtel-Dieu — Montreal, Quebec, Canada
• Royal Victoria Hospital - McGill University Health Centre — Montreal, Quebec, Canada
• Centre hospitalier affilié universitaire de Québec, Hôpital de l'Enfant-Jésus — Québec, Quebec, Canada

Full record on ClinicalTrials.gov

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