Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation

Recruiting now

Conditions studied: Lung Transplant Rejection

In brief

Objective: To evaluate the potential impact of molecular phenotyping of transbronchial biopsies in lung transplant recipients with allograft dysfunction, and the potential for developing a safer endobronchial mucosal biopsy format.

Key facts

Study ID

NCT02812290

Run by

University of Alberta

People needed

700

Starts

2016-05-01

Expected to finish

2027-12-01

Last updated by the study team

2026-05-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All lung transplant recipients undergoing a biopsy as determined by their surgeon or physician.

You may not qualify if…

• Patients who declined participation or unable to give informed consent.

Where it is running

• Department of Medicine, University of Alberta — Edmonton, Alberta, Canada (enrolling)
• Alberta Transplant Applied Genomics Centre, University of Alberta — Edmonton, Alberta, Canada (enrolling)
• Charles University/Hospital Motol — Prague, Czechia (enrolling)
• St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT — Phoenix, Arizona, United States (enrolling)
• The Alfred Hospital, Monash University — Melbourne, Australia
• Department of Thoracic Surgery, Medical University of Vienna — Vienna, Austria
• University Health Network, Toronto General Hospital — Toronto, Ontario, Canada
• Thoracic Surgery Transplant Clinic — Szczecin, Poland
• University of Maryland School of Medicine — Baltimore, Maryland, United States
• Division of Pulmonary and Critical Care, Washington University School of Medicine — St Louis, Missouri, United States
• University of Texas at San Antonio — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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