Trifecta-Lung cfDNA-MMDx Study

Recruiting now

Conditions studied: Lung Transplantation

In brief

Demonstrate the relationship between dd-cfDNA levels and HLA antibodies in blood transplant recipient and Demonstrate the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from lung transplants.

Key facts

Study ID

NCT05837663

Run by

University of Alberta

People needed

600

Starts

2023-11-01

Expected to finish

2028-12-01

Last updated by the study team

2026-07-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult, Older adult

You may not qualify if…

• Patients will be excluded from the study if they decline participation Are unable to give informed consent. Recipients of multiple organs, cancer patients and pregnant women

Where it is running

• Charles University/Hospital Motol — Prague, Czechia (enrolling)
• Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, College of Medicine — Gainesville, Florida, United States (enrolling)
• Mayo Clinic Florida, 4500 San Pablo Rd — Jacksonville, Florida, United States (enrolling)
• Motol University Hospital, V Uvalu 84 — Prague, Czechia (enrolling)
• St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT — Phoenix, Arizona, United States (enrolling)
• Indiana University Methodist Hospital 1812 N. Capitol Ave Suite W131L — Indianapolis, Indiana, United States (enrolling)
• Johns Hopkins Interventional Pulmonology, Sheikh Zayed Tower, Room 7125L, 1800 Orleans Street — Baltimore, Maryland, United States (enrolling)
• Division of Pulmonary, Allergy & Critical Care Medicine Columbia University Irving Medical Center — New York, New York, United States (enrolling)
• The Ohio State University Wexner Medical Center, 410 W 10th Ave — Columbus, Ohio, United States (enrolling)
• BAYLOR SCOTT & WHITE RESEARCH INSTITUTE , 3409 Worth Street — Dallas, Texas, United States (enrolling)
• UT Southwestern Medical Center, 5939 Harry Hines Blvd. — Dallas, Texas, United States (enrolling)
• Houston Methodist Lung Transplant Center, 6550 Fannin St., SM1001 — Houston, Texas, United States (enrolling)
• UT Health San Antonio 7703 Floyd Curl Drive, MSC: 7858 — San Antonio, Texas, United States (enrolling)
• The Alfred Hospital, Monash University — Melbourne, Australia (enrolling)
• Department of Medicine, University of Alberta — Edmonton, Alberta, Canada (enrolling)
• Alberta Transplant Applied Genomics Centre, University of Alberta — Edmonton, Alberta, Canada (enrolling)
• University Health Network, Toronto General Hospital — Toronto, Ontario, Canada (enrolling)
• USF Health, Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC40 — Tampa, Florida, United States
• Department of Thoracic Surgery, Medical University of Vienna — Vienna, Austria

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.