Toronto General Hospital

Toronto, Ontario ON M5G 2C4

20 studies enrolling now · 222 studies all time

What they study most

ARDS, Abdominal Aortic Aneurysm, Acquired Antithrombin Deficiency, Acute Coronary Syndrome, Acute Kidney Injury, Acute Respiratory Failure, Advanced Cancer, Alcoholic Hepatitis (AH), Anemia, Cooley's, Anorexia, Anorexia Nervosa, Antibiotic-associated Diarrhea

Studies at this site

• EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin) — Recruiting now
• A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis — Recruiting now
• Evaluation of A Clinical Diagnostic Test for CRDS — Recruiting now
• A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors — Recruiting now
• A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG) — Recruiting now
• A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis — Recruiting now
• Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass — Recruiting now
• The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C) — Recruiting now
• The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR — Recruiting now
• Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women — Recruiting now
• Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk — Recruiting now
• Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — Recruiting now
• An Adjuvant Study to Evaluate SMS001 (Paclitaxel) in Non-Small Cell Lung Cancer — Recruiting now
• Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance — Recruiting now
• Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure — Recruiting now
• Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery — Recruiting now
• Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia — Recruiting now
• A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease — Running, not enrolling
• FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression — Starting soon
• Pyruvate Kinase Deficiency Global Longitudinal Registry — Running, not enrolling
• Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function — Running, not enrolling
• Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease — Enrolling by invitation
• A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) — Completed
• A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) — Running, not enrolling
• A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis — Running, not enrolling
• Instylla HES Hypervascular Tumor Pivotal Study — Completed
• Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment. — Running, not enrolling
• AlloSure Lung Assessment and Metagenomics Outcomes Study — Running, not enrolling
• Pegcetacoplan Long Term Safety and Efficacy Extension Study — Completed
• The ECMO-Free Trial — Completed
• SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial — Running, not enrolling
• Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion — Running, not enrolling
• MitraClip REPAIR MR Study — Running, not enrolling
• Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis — Completed
• Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease — Completed
• A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment — Running, not enrolling
• An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM) — Enrolling by invitation
• Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial — Running, not enrolling
• AMPLATZER PFO Occluder Post Approval Study — Running, not enrolling
• A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE — Stopped early
• Olorofim Aspergillus Infection Study — Running, not enrolling
• A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy — Running, not enrolling
• A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia — Completed
• The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study — Running, not enrolling
• Active-control Randomized Trial Comparing 4-factor Prothrombin Complex Concentrate With Frozen Plasma in Cardiac Surgery — Completed
• CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM) — Running, not enrolling
• Hemodynamic-GUIDEd Management of Heart Failure — Completed
• EMPA-KIDNEY (The Study of Heart and Kidney Protection With Empagliflozin) — Completed
• Long Term Follow Up for CTSN Mitral Valve Repair Studies — Running, not enrolling
• A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection — Completed