The Retina Institute

St Louis, Missouri 63144

6 studies enrolling now · 44 studies all time

What they study most

Age - Related Macular Degeneration (AMD), Age Related Macular Degeneration, Age-related Macular Degeneration, Cataract, Central Retinal Vein Occlusion, Choroidal Neovascularization, DME, Diabetic Macular Edema, Diabetic Macular Edema (DME), Diabetic Retinopathy, Epiretinal Membrane, Full-thickness Macular Holes (MH)

Studies at this site

• CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME — Recruiting now
• Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD — Recruiting now
• A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251 — Recruiting now
• A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) — Recruiting now
• A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK — Recruiting now
• A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE — Recruiting now
• A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) — Completed
• A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56 — Running, not enrolling
• A Phase 2/3 Trial to Assess the Efficacy and Safety of OCU410ST for Stargardt Disease — Running, not enrolling
• Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy — Running, not enrolling
• Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD — Running, not enrolling
• A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab — Completed
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7497372 in Participants With Diabetic Macular Edema (DME) — Running, not enrolling
• 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration — Running, not enrolling
• Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration — Running, not enrolling
• A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 1) — Completed
• A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK — Running, not enrolling
• A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) — Completed
• Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration — Completed
• Comparing Post-intravitreal Injection Pain Scores Using Loteprednol, Bromfenac Sodium, and Artificial Tears Over a 24-hour Period — Completed
• The GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative Vitreoretinopathy — Completed
• Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration — Running, not enrolling
• DRCR.Net Aflibercept vs. Bevacizumab + Deferred Aflibercept for the Treatment of CI-DME — Completed
• A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD) — Stopped early
• A Phase 2 Study to Assess the Safety and Efficacy of Intravitreal ONL1204 Ophthalmic Solution in Subjects With Mac-off Retinal Detachment — Completed
• A Study Assessing the Long-Term Safety and Tolerability of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration — Stopped early
• Effects of Pneumatic Vitreolysis on Vitreomacular Traction — Completed
• A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema — Completed
• Effects of Pneumatic Vitreolysis on Macular Hole — Completed
• Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) — Completed
• Anti-VEGF vs. Prompt Vitrectomy for VH From PDR — Completed
• Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO — Stopped early
• PROMINENT-Eye Ancillary Study (Protocol AD) — Stopped early
• Treatment for CI-DME in Eyes With Very Good VA Study — Completed
• Safety and Tolerability Study of RO7171009 in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) — Completed
• A Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic Atrophy — Completed
• An Extension Study to Evaluate the Long-Term Safety of Lampalizumab in Participants With Geographic Atrophy — Stopped early
• Phase II Combination Steroid and Anti-VEGF for Persistent DME — Completed
• Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis Syndrome — Completed
• Ozurdex Implant for Macular Edema After Treatment Failure With Anti-VEGF — Stopped early
• Short-term Clinical Effects of Intravitreal Aflibercept Injection 2.0mg as a Predictor of Long-term Results — Status unconfirmed
• Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion — Completed
• Dexamethasone Intravitreal Implant After Vitrectomy For Epiretinal Membrane — Stopped early
• Age-Related Eye Disease Study 2 (AREDS2) — Completed