A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Recruiting now · Phase 2 · Has a placebo group
Conditions studied: Geographic Atrophy, Macular Degeneration
In brief
The purpose of this study is to assess the long-term safety and tolerability after an intravitreal injection (a shot of medicine into the eye) of JNJ-81201887 administered in parent clinical studies.
Key facts
- Study ID
- NCT06635148
- Run by
- Janssen Research & Development, LLC
- People needed
- 274
- Starts
- 2024-09-19
- Expected to finish
- 2030-07-16
- Last updated by the study team
- 2026-07-06
Who can join
Age: 60 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participants who were enrolled and received treatment with JNJ-81201887 or sham in a parent clinical study (81201887MDG2001, 81201887MDG1003)
- Females (women of childbearing potential), male participants, and partners of male participants will not be required to use contraception in this LTE study
- Must sign an informed consent form (ICF) indicating that participant understands the purpose of, and procedures required for, the study and is willing to participate in the study. The ICF may be signed by an impartial witness and/or legally designated representative depending on national/local regulations
You may not qualify if…
- There are no exclusion criteria for this LTE study
Where it is running
- Retina Consultants of Orange County — Fullerton, California, United States (enrolling)
- Shiley Eye Institute Jacobs Retina Center — La Jolla, California, United States (enrolling)
- California Retina Consultants — Oxnard, California, United States (enrolling)
- California Eye Medical Specialists — Pasadena, California, United States (enrolling)
- Retina Consultants San Diego — Poway, California, United States (enrolling)
- Bay Area Retina Associates — Walnut Creek, California, United States (enrolling)
- Retina Group of Florida — Fort Lauderdale, Florida, United States (enrolling)
- VitreoRetinal Associates, PA — Gainesville, Florida, United States (enrolling)
- Retina Specialty Institute — Pensacola, Florida, United States (enrolling)
- Retina Vitreous Associates of Florida — St. Petersburg, Florida, United States (enrolling)
- Georgia Retina — Marietta, Georgia, United States (enrolling)
- Marietta Eye Clinic — Marietta, Georgia, United States (enrolling)
- University Retina — Lemont, Illinois, United States (enrolling)
- Midwest Eye Institute — Carmel, Indiana, United States (enrolling)
- Maine Eye Center — Portland, Maine, United States (enrolling)
- Retina Specialists — Baltimore, Maryland, United States (enrolling)
- The Retina Group of Washington — Chevy Chase, Maryland, United States (enrolling)
- Cumberland Valley Retina Consultants — Hagerstown, Maryland, United States (enrolling)
- Ophthalmic Consultants of Boston — Boston, Massachusetts, United States (enrolling)
- Foundation for Vision Research — Grand Rapids, Michigan, United States (enrolling)
- Retina Consultants of Minnesota — Saint Louis Park, Minnesota, United States (enrolling)
- The Retina Institute — St Louis, Missouri, United States (enrolling)
- Sierra Eye Associates — Reno, Nevada, United States (enrolling)
- Retina-Vitreous Surgeons of Central New York — Liverpool, New York, United States (enrolling)
- Retina Associates Southwest PC — Tucson, Arizona, United States (enrolling)
Full record on ClinicalTrials.gov
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