Midwest Eye institute

Indianapolis, Indiana 46290

1 studies enrolling now · 48 studies all time

What they study most

"Wet" Age-Related Macular Degeneration, Age Related Macular Degeneration, Age-Related Macular Degeneration, Age-related Macular Degeneration, Anterior Ischemic Optic Neuropathy, Diabetes Mellitus, Diabetic Macular Edema, Diabetic Macular Edema (DME), Diabetic Retinopathy, Dry Age-related Macular Degeneration, Exudative Age-related Macular Degeneration, Eye Diseases

Studies at this site

• Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy — Recruiting now
• Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD — Running, not enrolling
• Fenofibrate for Prevention of DR Worsening — Running, not enrolling
• An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD — Completed
• A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema — Completed
• FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD — Stopped early
• Evaluation of Tonabersat for DME — Running, not enrolling
• A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) — Running, not enrolling
• A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor) — Completed
• Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy — Completed
• A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE) — Completed
• A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration — Running, not enrolling
• SOLACE Trial - A Phase 3 Trial in Subjects With Non-infectious Anterior-uveitis. — Completed
• Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD) — Completed
• Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment — Stopped early
• A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration — Completed
• The TIME-2b Study: A Study of AKB-9778 (Razuprotafib), a Novel Tie 2 Activator, in Patients With Non-Proliferative Diabetic Retinopathy (NPDR) — Completed
• Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration — Completed
• RBM-007 in Treatment naïve Exudative Age-related Macular Degeneration — Completed
• Safety and Tolerability Study of UBX1325 in Patients With Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration — Completed
• Safety and Effectiveness of Acthar Gel for Inflammation of the Eye's Uvea (Middle Layer) — Stopped early
• Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema — Completed
• Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO — Stopped early
• First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry Age Related Macular Degeneration — Completed
• Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degeneration — Completed
• Study of Pegcetacoplan (APL-2) Therapy in Patients With Geographic Atrophy — Completed
• A Study of Faricimab (RO6867461) in Participants With Center-Involving Diabetic Macular Edema — Completed
• A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME) — Completed
• A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Neovascular (Wet) Age-related Macular Degeneration — Completed
• PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) — Stopped early
• A Study to Determine if There is a Possible Association Between NAION and Phosphodiesterase Type 5 (PDE5) Inhibitors — Completed
• A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy — Completed
• Comparison of Age-related Macular Degeneration Treatments Trials: Lucentis-Avastin Trial — Completed
• Triamcinolone Acetonide Plus Laser Therapy to Treat Age-Related Macular Degeneration — Completed
• The Ranibizumab for Edema of the mAcula in Diabetes-2 (READ-2) Study — Completed
• Efficacy and Safety Study of iSONEP With & Without Lucentis/Avastin/Eylea to Treat Wet AMD — Completed
• A Phase 2, Multi-Center Study To Compare The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist With Ranibizumab In Adults With Diabetic Macular Edema — Stopped early
• Efficacy and Safety of Squalamine Lactate Eye Drops in Subjects With Neovascular (Wet) Age-related Macular Degeneration (AMD) — Completed
• Safety and Tolerability of NOVA63035 "Corticosteroid" in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy — Completed
• Study of Denufosol (INS37217) in Subjects With Rhegmatogenous Retinal Detachment — Stopped early
• Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-006) Trial. — Completed
• Seven Year Update of Macular Degeneration Patients — Completed
• A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis — Completed
• A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis — Completed
• Safety Study of iSONEP (Sonepcizumab/LT1009) to Treat Neovascular Age-related Macular Degeneration — Status unconfirmed
• Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD) — Completed
• A Study of MSI-1256F (Squalamine Lactate) To Treat "Wet" Age-Related Macular Degeneration — Stopped early
• A Safety and Efficacy Study of Squalamine Lactate for Injection (MSI-1256F) for "Wet" Age-Related Macular Degeneration — Stopped early