Evaluation of Tonabersat for DME
Running, not enrolling · Phase 2 · Has a placebo group
Conditions studied: Diabetic Macular Edema
In brief
This randomized clinical trial will evaluate the effect of tonabersat compared with placebo on central subfield thickness (CST) in eyes with center-involved diabetic macular edema (CI-DME) and good visual acuity.
Key facts
- Study ID
- NCT05727891
- Run by
- Jaeb Center for Health Research
- People needed
- 128
- Starts
- 2023-05-02
- Expected to finish
- 2026-01-01
- Last updated by the study team
- 2025-12-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Southeast Eye Institute, P.A. dba Eye Associates of Pinellas — Pinellas Park, Florida, United States
- Southeast Retina Center — Augusta, Georgia, United States
- Retina Associates of Southern California — Huntington Beach, California, United States
- Loma Linda University — Loma Linda, California, United States
- East Bay Retina Consultants, Inc. — Oakland, California, United States
- Southern California Desert Retina Consultants, Inc. — Palm Desert, California, United States
- Macula Retina Vitreous Institute — Torrance, California, United States
- National Ophthalmic Research Institute — Fort Myers, Florida, United States
- University of Florida- Jacksonville — Jacksonville, Florida, United States
- Central Florida Retina Institute — Lakeland, Florida, United States
- Florida Retina Consultants — Lakeland, Florida, United States
- Thomas Eye Group — Sandy Springs, Georgia, United States
- Illinois Retina Associates — Oak Park, Illinois, United States
- Midwest Eye Institute — Indianapolis, Indiana, United States
- Joseph E. Humble and Raymond Haik PTRS DBA Eye Assoc of Northeast Louisiana — West Monroe, Louisiana, United States
- Elman Retina Group — Baltimore, Maryland, United States
- Boston Medical Center Corporation — Boston, Massachusetts, United States
- Joslin Diabetes Center — Boston, Massachusetts, United States
- Mayo Clinic — Rochester, Minnesota, United States
- Retina Research Institute, LLC — St Louis, Missouri, United States
- Retina-Vitreous Surgeons of Central NY, PC — Liverpool, New York, United States
- Verum Research LLC — Eugene, Oregon, United States
- The Trustees of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
- Pittsburg Clinical Trial Consortium — Sewickley, Pennsylvania, United States
- Hilton Head Retina Institute — Hilton Head Island, South Carolina, United States
Full record on ClinicalTrials.gov
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