Dent Neurologic Institute

Amherst, New York 14226

7 studies enrolling now · 70 studies all time

What they study most

ALS, Acute Migraine, Aggression, Agitation, Agitation in Patients With Dementia of the Alzheimer's Type, Agitation,Psychomotor, Alzheimer Disease, Alzheimer's Disease, Alzheimer's Disease (AD), Alzheimer's Disease Dementia, Alzheimer's Disease Psychosis, Alzheimer's Type Dementia

Studies at this site

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight — Recruiting now
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight — Recruiting now
ACP-204 in Adults With Alzheimer's Disease Psychosis — Recruiting now
Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems — Recruiting now
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients — Recruiting now
Clinical Trial on Agitation in Alzheimer's Dementia — Recruiting now
Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type — Recruiting now
HEALEY ALS Platform Trial - Master Protocol — Running, not enrolling
Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS — Stopped early
A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes — Running, not enrolling
Study to Evaluate the Safety and Efficacy of PIPE-307 in Subjects With Relapsing-Remitting Multiple Sclerosis — Completed
Evaluation of Gadolinium Based Contrast Agents for Portable MR Imaging Systems — Enrolling by invitation
A Study to Learn About the Safety of Diranersen (BIIB080) Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age — Running, not enrolling
A Study of LY3841136 Compared With Placebo in Adult Participants With Obesity or Overweight — Completed
A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam) — Running, not enrolling
A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD — Running, not enrolling
A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight — Completed
A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight — Completed
A PIVOTAL STUDY EVALUATING SAFETY AND EFFICACY OF THE SHIRATRONICS MIGRAINE THERAPY SYSTEM — Running, not enrolling
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine — Running, not enrolling
A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine — Running, not enrolling
Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic Modeling — Stopped early
A Study of Suvecaltamide in Adults With Moderate to Severe Residual Tremor in Parkinson's Disease — Completed
A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2) — Completed
SUBLOCADE Long-term Outcomes — Completed
Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type — Stopped early
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2) — Running, not enrolling
Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated With Ozanimod (RPC-1063) — Stopped early
Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG) — Running, not enrolling
Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease — Completed
Open-label Extension for Phase 3 Clinical Trials of Simufilam — Stopped early
A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease — Stopped early
Serum Neurofilament Light in Multiple Sclerosis — Running, not enrolling
Alzheimer's Disease Neuroimaging Initiative 2 — Completed
Extension Study of ABP-20001 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 for Migraine Prevention — Stopped early
Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults — Completed
NRX-101 for Bipolar Depression With Subacute Suicidal Ideation — Completed
Phase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple Sclerosis — Stopped early
Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study — Completed
Phase 3 Study of OTO-104 in Subjects With Unilateral Meniere's Disease — Completed
PJ-011726 IntelliSpace Cognition MCI Study — Completed
Study of Lamotrigine to Treat Ménière's Disease — Completed
Lamotrigine and Bupropion for Meniere's Disease — Status unconfirmed
Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme(GBM) — Stopped early
12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Migraine in Participants With Episodic Migraine — Completed
An Extension Study to Evaluate the Efficacy and Safety of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS — Status unconfirmed
An Efficacy and Safety Evaluation of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS — Status unconfirmed
Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo — Completed
Inpatient, Dose-Ranging Study of Staccato Alprazolam in Epilepsy With Predictable Seizure Pattern — Completed
Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients With Motor Fluctuations — Stopped early