A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)
Running, not enrolling · Phase 2 · Has a placebo group
Conditions studied: Alzheimer Disease
In brief
The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine which may delay or slow the progression of the symptoms of early Alzheimer's disease.
Key facts
- Study ID
- NCT06223360
- Run by
- Alzheimer's Disease Cooperative Study (ADCS)
- People needed
- 406
- Starts
- 2024-03-28
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2026-06-04
Who can join
Age: 50 and older, up to 89. Sex: any. Healthy volunteers: not accepted.
Where it is running
- St. Joseph's Hospital and Medical Center/Barrow Neurological Institute — Phoenix, Arizona, United States
- Perseverance Research Center, LLC — Scottsdale, Arizona, United States
- Banner Sun Health Research Institute — Sun City, Arizona, United States
- The Neuron Clinic — Chula Vista, California, United States
- University of California, Irvine — Irvine, California, United States
- Pacific Research Network — Lemon Grove, California, United States
- University of Southern California — Los Angeles, California, United States
- Cedars Sinai, Los Angeles — Los Angeles, California, United States
- Syrentis Clinical Research — Santa Ana, California, United States
- JEM Research Institute — Atlantis, Florida, United States
- Brain Matters Research — Delray Beach, Florida, United States
- Neuropsychiatric Research Center of Southwest Florida — Fort Myers, Florida, United States
- CCM Clinical Research Group, LLC — Miami, Florida, United States
- Gonzalez MD & Aswad MD Health Services — Miami, Florida, United States
- Miami Jewish Health — Miami, Florida, United States
- Blue Medical Research Inc. — Miami, Florida, United States
- Brainstorm Research — Miami, Florida, United States
- Brain Matters Research (Kane Center) — Stuart, Florida, United States
- Conquest Research — Winter Park, Florida, United States
- Emory University Goizueta Alzheimer's Disease Research Center(GADRC) — Atlanta, Georgia, United States
- Sandhill Research, LLC d/b/a Accel Research Sites — Decatur, Georgia, United States
- Northwestern University Feinberg School of Medicine — Chicago, Illinois, United States
- Rush University Medical Center — Chicago, Illinois, United States
- Southern Illinois University — Springfield, Illinois, United States
- University of Iowa — Iowa City, Iowa, United States
Full record on ClinicalTrials.gov
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