Cleveland Clinic-Main Campus

Cleveland, Ohio 44195

25 studies enrolling now · 82 studies all time

What they study most

Abdominal Pain, Abdominal Surgery, Abdominal Wall Defect, Abdominal Wall Hernia, Active Idiopathic Inflammatory Myopathy, Advanced Solid Tumor, Advanced Urothelial Carcinoma, Alzheimer's Disease, Amyloid Cardiomyopathy, Transthyretin-Related, Anal Erosion, Antimicrobial Stewardship, Antisynthetase Syndrome

Studies at this site

• Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease — Recruiting now
• Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) — Recruiting now
• Visugromab in Cachexia International Trial — Recruiting now
• A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) — Recruiting now
• A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma — Recruiting now
• Cardiovascular and Metabolic Sciences Biorepository — Recruiting now
• Dietary Tracking in Heart Failure — Recruiting now
• Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients — Recruiting now
• Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH) — Recruiting now
• A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis — Recruiting now
• Preoperative Weight Loss for Open Abdominal Wall Reconstruction — Recruiting now
• Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome — Recruiting now
• EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD) — Recruiting now
• Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes — Recruiting now
• Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery — Recruiting now
• Suture Repair vs Mesh Repair for Incisional Hernia — Recruiting now
• Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease — Recruiting now
• Preoperative BOTOX® Injection for Large Ventral Hernia Repair — Recruiting now
• The GUARDIAN Trial — Recruiting now
• Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy — Recruiting now
• Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW) — Running, not enrolling
• A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy. — Completed
• Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension — Running, not enrolling
• A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7) — Running, not enrolling
• HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer — Running, not enrolling
• REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels — Running, not enrolling
• Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer — Running, not enrolling
• Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia — Completed
• Analysis of MicroBial Metabolites After Eating Refined Food — Completed
• Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo) — Running, not enrolling
• Glycemic Control, Type II Diabetes, Parathyroidectomy — Running, not enrolling
• DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2) — Running, not enrolling
• Intravenous Oliceridine and Opioid-related Complications — Completed
• The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry) — Enrolling by invitation
• Rotator Cuff Failure With Continuity — Running, not enrolling
• Herbs & Supplements in Breast Cancer Usage, Impact, and Personalized Approaches for Diverse Populations — Starting soon
• An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM) — Enrolling by invitation
• Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures — Running, not enrolling
• A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform — Completed
• Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia With Lewy Bodies — Completed
• DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02] — Completed
• Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator — Stopped early
• A Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors — Stopped early
• Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations — Running, not enrolling
• A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis — Stopped early
• The CARDIO-TTRansform Scintigraphy Sub-study — Running, not enrolling
• Clinical Trial of SOT102 Antibody Drug Conjugate in Patients With Advanced Gastric and Pancreatic Adenocarcinoma — Stopped early
• Study of the Safety and Effectiveness of Motiva Implants® — Running, not enrolling
• A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes — Completed
• Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants — Running, not enrolling