Centre hospitalier de l'Université de Montréal (CHUM)

Montreal, Quebec PO 25223

8 studies enrolling now · 40 studies all time

What they study most

Adrenocortical Carcinoma, Advanced Cancer, Advanced Solid Tumor, Antimicrobial, Asthma, Bacteremia, Bladder Cancer, Breast Cancer, Breast Cancer Female, COVID-19, Cirrhosis, Community-acquired Pneumonia

Studies at this site

• A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer — Recruiting now
• EXtubation Related Complications - the EXTUBE Study (EXTUBE) — Recruiting now
• Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation — Recruiting now
• International Registry for Men With Advanced Prostate Cancer (IRONMAN) — Recruiting now
• Platform of Randomized Adaptive Clinical Trials in Critical Illness — Recruiting now
• AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia — Recruiting now
• Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study — Recruiting now
• EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD) — Recruiting now
• Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer — Running, not enrolling
• Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis — Stopped early
• A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer) — Running, not enrolling
• Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC — Running, not enrolling
• An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM) — Enrolling by invitation
• Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial — Running, not enrolling
• Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure — Running, not enrolling
• Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40% — Completed
• MANTIS Endoscopic Clipping Study — Completed
• A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC) — Stopped early
• CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM) — Running, not enrolling
• A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE) — Completed
• A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness — Completed
• TH1902 in Patients With Advanced Solid Tumors — Running, not enrolling
• AB-16B5 Combined With Docetaxel in Subjects With Metastatic Non-Small Cell Lung Cancer (EGIA-002) — Completed
• Zoster Eye Disease Study — Completed
• A Study of OSI-906 in Patients With Locally Advanced or Metastatic Adrenocortical Carcinoma — Completed
• A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley) — Stopped early
• Development of a New Canadian Endourology Group Stent Symptom Score — Status unconfirmed
• A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors — Stopped early
• A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's Disease — Completed
• Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness — Completed
• An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored Studies — Completed
• Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones — Completed
• A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi — Completed
• Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors — Running, not enrolling
• Antithrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC) — Completed
• Study of DPX-Survivac Therapy in Patients With Recurrent Ovarian Cancer — Status unconfirmed
• Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis — Completed
• A Study to Evaluate Changes in Human Breast Cancer Tissue Following Short-Term Use of Darolutamide — Completed
• Study to Evaluate 99mTc-MIP-1404 SPECT/CT Imaging in Men With Biopsy Proven Low-Grade Prostate Cancer — Completed
• Longitudinal Cohort Study in Participants With Severe Asthma to Assess Biomarkers — Completed