Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones

Completed · Not applicable

Conditions studied: Kidney Stone

In brief

Pain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation. Non-obstructing renal calculi that do not cause renal collecting system dilatation are thought to be painless. The objective of this study is to prospectively determine if the removal of non-obstructing renal calculi can reduce or eliminate participant's pain and/or improve their quality of life.

Key facts

Study ID

NCT03657667

Run by

Centre hospitalier de l'Université de Montréal (CHUM)

People needed

43

Starts

2018-08-28

Expected to finish

2023-03-09

Last updated by the study team

2023-04-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with renal colic and non-obstructing renal calculi. No stone greater than 10 mm in longest diameter
• All other causes of pain have been eliminated (by clinical judgment; if the cause of pain is in doubt: assessment by a family doctor or medical specialist will be obtained)
• Patients older than 18 years old
• Moderate to severe pain (> or = 5 on BPI pain scale: pain at its worst in the last 24hrs)

You may not qualify if…

• Patient's with anatomic abnormalities (calyceal diverticulum)
• Ureteral calculi
• Nephrocalcinosis
• RTA, medullary sponge kidney, sarcoidosis
• Hydronephrosis or hydrocalycosis
• Minimal pain (<5 on BPI pain scale: pain at its worst in the last 24 hrs)

Where it is running

• University of California, Davis — Davis, California, United States
• University of California, San Diego — San Diego, California, United States
• Indiana University — Bloomington, Indiana, United States
• Brigham And Women's Hospital — Boston, Massachusetts, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• Milton S. Hershey Medical Center — Hershey, Pennsylvania, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States
• Baylor Scott and White Health — Temple, Texas, United States
• Centre Hospitalier de l'université de Montréal (CHUM) — Montreal, Quebec, Canada

Full record on ClinicalTrials.gov

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