The hospital for sick children

Toronto M5G 1X8

6 studies enrolling now · 41 studies all time

What they study most

Achondroplasia, Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Adenovirus Infections, Atypical Hemolytic Uremic Syndrome, Beta-Thalassemia, Biliary Atresia, Crohn's Disease, Cystic Fibrosis, Diamond Blackfan Anemia, Genetic Diseases, Inborn

Studies at this site

• A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease — Recruiting now
• A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON) — Recruiting now
• A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT — Recruiting now
• A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation — Recruiting now
• Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block — Recruiting now
• Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow — Running, not enrolling
• An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia — Enrolling by invitation
• Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD) — Completed
• A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis — Completed
• Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age — Running, not enrolling
• Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells — Enrolling by invitation
• Long Term Safety & Efficacy Study Evaluating The Effect of A4250 in Children With PFIC — Completed
• Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma — Completed
• Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older — Completed
• Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF) — Completed
• A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia — Completed
• This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC Types 1 or 2 — Completed
• Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy — Stopped early
• A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy — Completed
• Registry of Pediatric Orthopedic Trauma and Health Outcomes in Skeletally Immature Children — Running, not enrolling
• A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease — Completed
• Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy — Completed
• Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older — Completed
• Observational Study Investigating Clinical & Anthropometric Characteristics of Children With Achondroplasia. — Stopped early
• Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation — Completed
• A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders — Completed
• Phase I/II Study of Avelumab in Pediatric Cancer Participants — Stopped early
• Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR) — Completed
• A Safety, Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis — Stopped early
• Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years — Completed
• Trial to Evaluate Efficacy and Safety of Lenabasum in Cystic Fibrosis — Completed
• Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Participants 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del — Completed
• PEACE: Pediatric Antifungal Comparative Effectiveness — Completed
• Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age — Completed
• A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Still's Disease (SJIA and AOSD) — Stopped early
• A Phase 3 Study of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) — Completed
• Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary Immunodeficiency — Completed
• aHUS Observational Long Term Follow-Up — Stopped early
• Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy — Completed
• More Frequent In-Center Hemodialysis in Pediatric End Stage Renal Disease — Completed
• Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload — Completed