Duke Eye center

Durham, North Carolina 27710

12 studies enrolling now · 73 studies all time

What they study most

Age - Related Macular Degeneration (AMD), Age Related Macular Degeneration, Age-Related Macular Degeneration, Age-related Macular Degeneration, Brain Neoplasms, Brain Neoplasms, Primary, Carcinoma, Non-Small-Cell Lung, Central Retinal Vein Occlusion, Choroideremia, Coats' Disease, Develop and Test Robotically Assisted Imaging System for the Front of the Eye, Diabetic Macular Edema

Studies at this site

• A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults — Recruiting now
• A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA) — Recruiting now
• Robotic OCT for ER Anterior Eye Exams — Recruiting now
• Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD — Recruiting now
• A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251 — Recruiting now
• A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS) — Recruiting now
• A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) — Recruiting now
• Automated Applanation Tonometry - Updated — Recruiting now
• Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2 — Recruiting now
• An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene — Recruiting now
• AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance — Recruiting now
• A Phase 2/3 Trial to Assess the Efficacy and Safety of OCU410ST for Stargardt Disease — Running, not enrolling
• Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy — Running, not enrolling
• A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME — Running, not enrolling
• Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene — Running, not enrolling
• A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis Pigmentosa — Running, not enrolling
• An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration — Running, not enrolling
• Tolerability of an Anesthesia-free Tonometer Tip — Completed
• Study of PF-07265807 in Participants With Metastatic Solid Tumors. — Stopped early
• 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration — Running, not enrolling
• An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED) — Running, not enrolling
• NT-101 Topical Ophthalmic Solution in Patients With Wet AMD — Completed
• Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects — Completed
• Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration — Running, not enrolling
• Reliability and Reproducibility of the Eye Check Tonometer — Stopped early
• DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia — Completed
• A Study in Subjects With Retinitis Pigmentosa — Completed
• Vamikibart in Participants With Uveitic Macular Edema — Completed
• An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED) — Running, not enrolling
• A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP — Running, not enrolling
• A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm — Completed
• Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene — Completed
• Compact Auto-Aligning Multi-Modal Eye Imaging to Diagnose Traumatic Eye Injury — Starting soon
• HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005 — Stopped early
• A Study of Yutiq Steroid Insert During Glaucoma Tube Implant Surgery — Running, not enrolling
• Imaging Parameters and DME Treatment Response — Completed
• A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement — Stopped early
• Evaluation of the Heidelberg Engineering SPECTRALIS With Flex Module for In-vivo Imaging in the Supine Position — Completed
• A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration — Running, not enrolling
• Automated Applanation Tonometry — Stopped early
• A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101 — Completed
• Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP) — Completed
• The Baerveldt Versus ClearPath Comparison Study — Completed
• ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA — Completed
• Safety and Efficacy of Emixustat in Stargardt Disease — Completed
• A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis — Completed
• The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study — Withdrawn before enrolling
• Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension — Completed
• SD-OCT Angiography — Stopped early
• Photodynamic Therapy for PDA in NV AMD — Completed