Cleveland Clinic Lou Ruvo Center for Brain health

Las Vegas, Nevada 891060100

3 studies enrolling now · 43 studies all time

What they study most

Alzheimer Disease, Alzheimer's Disease, Alzheimer's Disease (AD), Alzheimers Disease, Amyloid Plaque, Amyotrophic Lateral Sclerosis, Atypical Parkinsonism, Behavioral Variant Frontotemporal Dementia (bvFTD), C9orf72, Cognition Disorders, Cognitive Decline, Cognitive Dysfunction

Studies at this site

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) — Recruiting now
• PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort — Recruiting now
• A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease — Recruiting now
• MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients — Completed
• AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid — Running, not enrolling
• Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition — Stopped early
• RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies — Completed
• AMX0035 and Progressive Supranuclear Palsy — Completed
• A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP) — Completed
• A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease — Running, not enrolling
• Alzheimer's Disease Neuroimaging Initiative 3 — Completed
• A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease — Running, not enrolling
• A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease — Running, not enrolling
• Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS — Running, not enrolling
• A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease — Stopped early
• A Study to Evaluate Safety and Tolerability of Aducanumab in Participants With Alzheimer's Disease Who Had Previously Participated in the Aducanumab Studies 221AD103, 221AD301, 221AD302 and 221AD205 — Stopped early
• Alzheimer's Disease Neuroimaging Initiative 2 — Completed
• TRC-PAD Program: In-Clinic Trial-Ready Cohort — Completed
• A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration — Completed
• Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study — Completed
• Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia With Lewy Bodies — Completed
• GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease — Completed
• Exercise in Adults With Mild Memory Problems — Completed
• Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease — Stopped early
• Assessment of Tecfidera® in Radiologically Isolated Syndrome (RIS) — Completed
• Utilization of Target Ranges to Treat Parkinson's Disease With the PKG — Stopped early
• 221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease — Stopped early
• AC-1204 26-Week Long Term Efficacy Response Trial With Optional Open-label Ext — Completed
• A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease — Stopped early
• Study of Ozanimod (RPC1063) in Relapsing Multiple Sclerosis (MS) — Completed
• Rasagiline Rescue in Alzheimer's Disease Clinical Trial — Completed
• Clinical Evaluation of Flortaucipir F 18 — Completed
• Tau Imaging in Professional Fighters — Completed
• Study of Urate Elevation in Parkinson's Disease, Phase 3 — Completed
• Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease (US202) — Completed
• Resveratrol for Alzheimer's Disease — Completed
• Amyloid Imaging And Safety Study Of ACC-001 In Subjects With Early Alzheimer's Disease — Completed
• Bexarotene Amyloid Treatment for Alzheimer's Disease — Completed
• A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease — Stopped early
• Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Carrier) — Completed
• Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Non-Carrier) — Completed
• Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease — Completed
• Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center — Completed