Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease
Stopped early · Phase 2 · Has a placebo group
Conditions studied: Alzheimer's Disease
In brief
The primary objective of the placebo-controlled period is to evaluate the safety and tolerability of BIIB092 in participants with mild cognitive impairment (MCI) due to Alzheimer's disease (AD) or with mild AD. The secondary objectives of the placebo-controlled period are to evaluate the efficacy of multiple doses of BIIB092 in slowing cognitive and functional impairment in participants with MCI due to AD or with mild AD, and to evaluate the immunogenicity of BIIB092 after multiple doses in participants with MCI due to AD or with mild AD. The primary objective of the long-term extension period is to evaluate the long-term safety and tolerability of BIIB092 in participants with MCI due to AD or with mild AD.
Key facts
- Study ID
- NCT03352557
- Run by
- Biogen
- People needed
- 654
- Starts
- 2018-05-03
- Expected to finish
- 2021-08-30
- Last updated by the study team
- 2022-11-08
Who can join
Age: 50 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Xenoscience Inc — Phoenix, Arizona, United States
- Banner Alzheimer's Institute — Phoenix, Arizona, United States
- Dignity Health — Phoenix, Arizona, United States
- Banner Sun Health Research Institute — Sun City, Arizona, United States
- Advanced Research Center, Inc. — Anaheim, California, United States
- The Research Center of Southern California — Carlsbad, California, United States
- Positron Research International — Fremont, California, United States
- Neuropain Medical Center — Fresno, California, United States
- V Royter, MD, APMC — Hanford, California, United States
- Irvine Center for Clinical Research, Inc. — Irvine, California, United States
- Research Center for Clinical Studies West — Lancaster, California, United States
- Mary S. Easton Center for Alzheimer's Disease Research, UCLA — Los Angeles, California, United States
- Hoag Memorial Hospital Presbyterian — Newport Beach, California, United States
- Stanford Hospital and Clinics — Palo Alto, California, United States
- Pacific Research Network, Inc — San Diego, California, United States
- Syrentis Clinical Research — Santa Ana, California, United States
- Invicro — New Haven, Connecticut, United States
- Yale University School Of Medicine — New Haven, Connecticut, United States
- JEM Research Institute — Atlantis, Florida, United States
- Brain Matters Research — Delray Beach, Florida, United States
- Neuropsychiatric Research Center of Southwest Florida — Fort Myers, Florida, United States
- Renstar Medical Research — Ocala, Florida, United States
- Synexus Clinical Research US, Inc. - Orlando — Orlando, Florida, United States
- Progressive Medical Research — Port Orange, Florida, United States
- University of Alabama at Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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