Washington University School of Medicine/St. Louis Children's Hospital

St Louis, Missouri 63310

4 studies enrolling now · 26 studies all time

What they study most

Acute Lung Injury, Acute Lymphoblastic Leukemia, Alagille Syndrome, Alpha 1-Antitrypsin Deficiency, Asymmetric Hearing Loss, Brain Tumor, Cystic Fibrosis, Early-Onset Scoliosis Deformity of Spine, Glioma, H3 K27M, Hemiparesis, Liver Diseases

Studies at this site

• Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients — Recruiting now
• Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i) — Recruiting now
• A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1) — Recruiting now
• ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) — Recruiting now
• A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy — Running, not enrolling
• Asciminib With or Without Sildenafil for Brain Tumors — Starting soon
• Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) — Paused
• Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE) — Completed
• Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age — Running, not enrolling
• Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial — Running, not enrolling
• Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older — Completed
• Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals — Running, not enrolling
• A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF) — Completed
• Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome — Completed
• Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy — Completed
• A Study Evaluating the Long-term Safety of VX-445 Combination Therapy — Completed
• Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years — Completed
• L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects — Completed
• A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis — Completed
• A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy — Stopped early
• A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes) — Completed
• A Phase 3 Study of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) — Completed
• A Study of VX-659 Combination Therapy in CF Subjects Homozygous for F508del (F/F) — Completed
• Hypotonia and Neurofibromatosis Type 1 (NF1) Glioma — Stopped early
• A Rehabilitation Program in Children With Sickle Cell Disease and Cognitive Deficits: a Pilot Study — Completed
• The EPIC Observational Study — Completed