Sheba medical center

Tel Litwinsky 58291

8 studies enrolling now · 57 studies all time

What they study most

Acute Lymphoblastic Leukemia (ALL), Anemia, Angina Pectoris, Aortic Stenosis, Aortic Valve Disease, B-Cell Chronic Lymphocytic Leukemia, B-Cell Malignancies, B-cell Chronic Lymphocytic Leukemia, Bone Metastases, Bradycardia, Brain Metastases, Breast Cancer

Studies at this site

• Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs) — Recruiting now
• Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome — Recruiting now
• Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers — Recruiting now
• A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma — Recruiting now
• Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry — Recruiting now
• Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01) — Recruiting now
• Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation — Recruiting now
• FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3 — Recruiting now
• MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) — Recruiting now
• A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery — Running, not enrolling
• Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) — Running, not enrolling
• Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465) — Running, not enrolling
• Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN) — Running, not enrolling
• A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia — Completed
• A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer — Running, not enrolling
• A Registry for BRCA Mutation Carriers With Pancreatic Ductal Adenocarcinoma — Running, not enrolling
• A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma. — Running, not enrolling
• Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments — Running, not enrolling
• An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia — Completed
• Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy — Completed
• DOAC in Unusual Site Venous Thrombosis — Completed
• Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia — Completed
• Nodal Burden and Nodal Recurrence in Patients With Isolated Tumor Cells After Neoadjuvant Chemotherapy Treated With Axillary Dissection or Nodal Radiation: the OPBC-05/EUBREAST-14R/ICARO Study — Completed
• Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF — Completed
• TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence — Status unconfirmed
• Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Telangiectasia Patients — Completed
• Safety of Ruconest in 2-13 Year Old Hereditary Angioedema (HAE) Patients — Completed
• Sorin Universal REgistry on Aortic Valve Replacement — Stopped early
• A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer — Completed
• A Study Evaluating the Long-term Safety of VX-445 Combination Therapy — Completed
• A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety — Completed
• Evaluation of Activity and Safety of Oral Selinexor in Participants With Severe COVID-19 Infection — Completed
• AURORA: A Study for the Efficacy and Safety of Cenicriviroc (CVC) for the Treatment of Liver Fibrosis in Adults With Nonalcoholic Steatohepatitis (NASH) — Stopped early
• A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy — Stopped early
• A Study to Evaluate the Efficacy and Safety of Lenalidomide as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Following Second Line Therapy — Completed
• Age of Blood in Children in Pediatric Intensive Care Units — Completed
• A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain — Completed
• Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer — Completed
• A Phase 3 Study of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) — Completed
• ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain — Completed
• ImageReady(TM) MR Conditional Pacing System Clinical Study — Completed
• Study Of The Effectiveness & Safety Of Lenalidomide Versus Chlorambucil As First Line Therapy For Elderly Patients With B-Cell CLL (The ORIGIN Trial) — Completed
• Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA) — Completed
• A Study to Determine the Efficacy and Safety of Lenalidomide in Patients With Mantle Cell NHL Who Have Relapsed or Progressed After Treatment With Bortezomib or Are Refractory to Bortezomib. The "EMERGE" Trial — Completed
• Safety and Efficacy of IZN-6N4 Oral Rinse for the Prevention of Oral Mucositis in Patients With Head and Neck Cancer — Completed
• Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT) — Stopped early
• Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma — Completed
• Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI) — Completed
• A Study Comparing Bevacizumab Therapy With or Without Erlotinib for First-Line Treatment of Non-Small Cell Lung Cancer (ATLAS) — Completed
• 26 Week Efficacy and Safety Trial for Patients With Chronic Idiopathic Constipation — Stopped early