Ottawa Hospital Research Institute

Ottawa, Ontario K1y 4e9

10 studies enrolling now · 47 studies all time

What they study most

ARDS, Acute Ischemic Stroke, Advanced Solid Tumors, Amyotrophic Lateral Sclerosis, Anxiety Disorder, Arthrodesis Surgery Involving the Hindfoot or Ankle, Atherosclerosis, COPD, COVID-19, Cancer, Carcinoma, Hepatocellular, Cardiovascular Disease

Studies at this site

• A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer — Recruiting now
• Falls Validation Study — Recruiting now
• International Care Bundle Evaluation in Cerebral Hemorrhage Research — Recruiting now
• Study of BB-031 in Acute Ischemic Stroke Patients (RAISE) — Recruiting now
• Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD) — Recruiting now
• Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2 — Recruiting now
• Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology — Recruiting now
• myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home — Recruiting now
• Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma — Recruiting now
• Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer — Running, not enrolling
• A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients — Running, not enrolling
• A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC) — Completed
• A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer) — Running, not enrolling
• Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer — Completed
• NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer — Completed
• Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial — Running, not enrolling
• Efficacy and Safety of Losmapimod in Treating Subjects With Facioscapulohumeral Muscular Dystrophy (FSHD) With Open-Label Extension (OLE) — Stopped early
• Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC — Running, not enrolling
• Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma. — Completed
• A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301 — Enrolling by invitation
• Lipoic Acid for Progressive Multiple Sclerosis (MS) — Completed
• A Study to Evaluate the Impact of Apremilast on Magnetic Resonance Imaging (MRI) Outcomes in Adults With Psoriatic Arthritis — Completed
• A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY) — Running, not enrolling
• Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Participants With Early Stage Relapsing Remitting Multiple Sclerosis (RRMS) — Stopped early
• A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC Vs. Placebo + SOC in Adult Hospitalized Patients with COVID-19 — Paused
• Validation of Handheld Ultrasound Devices in Rheumatology — Completed
• EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial) — Running, not enrolling
• A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031) — Stopped early
• Efficacy and Safety of Losmapimod in Subjects With Facioscapulohumeral Muscular Dystrophy (FSHD) — Completed
• A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's Disease — Completed
• Nivolumab Ipilimumab in Patients With hyperMutated Cancers Detected in Blood (NIMBLe) — Stopped early
• A Study of RVT-1401 in Myasthenia Gravis (MG) Patients — Completed
• A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer — Completed
• A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma — Completed
• An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored Studies — Completed
• Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer — Completed
• This is a Trial of MG1-E6E7 With Ad-E6E7 and Atezolizumab in Patients With HPV Associated Cancers — Stopped early
• A Pivotal Study to Assess the InSpace™ Device for Treatment of Full Thickness Massive Rotator Cuff Tears — Completed
• AMPLEX Ankle Fusion and Hindfoot — Completed
• Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2) — Stopped early
• Safely Ruling Out Deep Vein Thrombosis in Pregnancy With the LEFt Clinical Decision Rule and D-Dimer — Status unconfirmed
• Safety and Tolerability of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients With Parkinson's Disease. — Stopped early
• A Efficacy and Safety Study of R935788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP) — Completed
• Carotid Revascularization Endarterectomy Versus Stenting Trial — Completed
• Predicting Bleeding Risk on Anticoagulant Therapy for Venous Thromboembolism — Completed
• A Cooperative Clinical Study of Abatacept in Multiple Sclerosis — Completed
• SDX-105 in Combination With Rituxan for Patients With Relapsed Indolent or Mantle Cell Non-Hodgkin's Lymphoma (NHL) — Completed