Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer
Completed · Phase 2
Conditions studied: Fallopian Tube Cancer, Metastatic Cancer, Ovarian Cancer, Peritoneal Cavity Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, carboplatin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving them in different ways may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating patients with ovarian epithelial cancer, primary peritoneal cancer, and fallopian tube cancer. PURPOSE: This randomized phase II trial is comparing the side effects of three combination chemotherapy regimens and to see how well they work in treating patients with stage IIB, stage IIC, stage III, or stage IV ovarian epithelial cancer, primary peritoneal cancer, or fallopian tube cancer.
Key facts
- Study ID
- NCT00993655
- Run by
- Canadian Cancer Trials Group
- People needed
- 275
- Starts
- 2010-03-03
- Expected to finish
- 2016-07-11
- Last updated by the study team
- 2023-08-28
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
Where it is running
- Mercy-Springfield — Springfield, Missouri, United States
- CoxHealth — Springfield, Missouri, United States
- University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
- Women and Infants Hospital of Rhode Island — Providence, Rhode Island, United States
- Univ of Utah (Huntsman Cancer Institute) — Salt Lake City, Utah, United States
- Northwest CCOP - Multicare Health System — Tacoma, Washington, United States
- Tom Baker Cancer Centre — Calgary, Alberta, Canada
- Cross Cancer Institute — Edmonton, Alberta, Canada
- BCCA - Cancer Centre for the Southern Interior — Kelowna, British Columbia, Canada
- BCCA - Fraser Valley Cancer Centre — Surrey, British Columbia, Canada
- BCCA - Vancouver Cancer Centre — Vancouver, British Columbia, Canada
- CancerCare Manitoba — Winnipeg, Manitoba, Canada
- Regional Health Authority B, Zone 2 — Saint John, New Brunswick, Canada
- Dr. H. Bliss Murphy Cancer Centre — St. John's, Newfoundland and Labrador, Canada
- QEII Health Sciences Centre — Halifax, Nova Scotia, Canada
- Cancer Centre of Southeastern Ontario at Kingston — Kingston, Ontario, Canada
- London Regional Cancer Program — London, Ontario, Canada
- Ottawa Hospital Research Institute — Ottawa, Ontario, Canada
- Thunder Bay Regional Health Science Centre — Thunder Bay, Ontario, Canada
- Univ. Health Network-Princess Margaret Hospital — Toronto, Ontario, Canada
- Hopital Maisonneuve-Rosemont — Montreal, Quebec, Canada
- CHUM - Hopital Notre-Dame — Montreal, Quebec, Canada
- McGill University - Dept. Oncology — Montreal, Quebec, Canada
- CHUQ-Pavillon Hotel-Dieu de Quebec — Québec, Quebec, Canada
- Centre hospitalier universitaire de Sherbrooke — Sherbrooke, Quebec, Canada
Full record on ClinicalTrials.gov
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