Wake Forest University-Baptist Medical Center

Winston-Salem, North Carolina 27157-1082

6 studies enrolling now · 147 studies all time

What they study most

Acute Compartment Syndrome, Acute Coronary Syndrome, Acute Lung Injury, Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive), Acute Myocardial Infarction, Acute Respiratory Failure, Adult Lower Limb Spasticity, Aging, Alcoholism, Alpha 1-Antitrypsin Deficiency, Alpha1-Antitrypsin Deficiency, Amputation

Studies at this site

• Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD — Recruiting now
• An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) — Recruiting now
• A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) — Recruiting now
• A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis — Recruiting now
• PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation — Recruiting now
• Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture) — Recruiting now
• A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients. — Running, not enrolling
• Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease — Running, not enrolling
• A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis — Running, not enrolling
• Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment. — Running, not enrolling
• A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer — Running, not enrolling
• A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP — Running, not enrolling
• Assessment of Fixation Strategies for Severe Open Tibia Fractures — Completed
• Transtibial Amputation Outcomes Study — Completed
• Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD — Running, not enrolling
• Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage — Completed
• Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Extreme Risk Subjects Who Need Aortic Valve Replacement — Completed
• Sleep for Stroke Management and Recovery Trial — Running, not enrolling
• DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03] — Running, not enrolling
• Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome — Completed
• Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation — Completed
• Nutrition and Exercise in Critical Illness — Completed
• A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness — Completed
• Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome — Completed
• Impact of Discontinuing Chronic Therapies in People With Cystic Fibrosis on Highly Effective CFTR Modulator Therapy — Completed
• Multicenter Study of Patient-reported Gastrointestinal Symptoms in People With Cystic Fibrosis — Completed
• Efficacy and Safety Study of Intravenous Progesterone in Patients With Severe Traumatic Brain Injury — Completed
• Evaluation of a Diagnostic Device for Detection of Nasal Staphylococcus Aureus — Completed
• Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation — Completed
• Prospective Huntington At Risk Observational Study — Completed
• Phase 3 Study to Treat Patients With Soft Tissue Sarcomas — Completed
• PREVENTion of Clot in Orthopaedic Trauma — Completed
• Regional Versus General Anesthesia for Promoting Independence After Hip Fracture — Completed
• A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer — Completed
• Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS) — Completed
• Digihaler in Chronic Obstructive Pulmonary Disease (COPD) — Completed
• Observational Study Comparing Home to Office Spirometry — Completed
• 3 TPV/RTV Doses in Multiple ARV Experienced Patients - Tipranavir Dose Defining Study — Completed
• Topiramate for Cryptogenic Sensory Peripheral Neuropathy in Metabolic Syndrome (CSPN) — Completed
• XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort — Completed
• ABSORB III Randomized Controlled Trial (RCT) — Completed
• Residual Anti-Xa Activity After Last Treatment Dose of Enoxaparin — Stopped early
• TARGET BP I Clinical Trial — Running, not enrolling
• Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen — Completed
• A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection — Stopped early
• Pediatric Hypertension Registry (PHREG) — Stopped early
• A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis — Completed
• A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure — Completed
• Streamlining Trauma Research Evaluation With Advanced Measurement — Completed
• Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label Extension — Stopped early