The University of Texas Health Science Center at Tyler

Tyler, Texas 75708-3154

4 studies enrolling now · 31 studies all time

What they study most

Alpha 1-Antitrypsin Deficiency, Alpha 1-antitrypsin Deficiency (AATD), Alpha-1 Antitrypsin Deficiency (AATD), Alpha1-Antitrypsin Deficiency, Alpha1-antitrypsin Deficiency, Breast Cancer, Bronchiectasis, COVID-19, Carcinoma, Non-Small-Cell Lung, Covid19, Crohn Disease, Cystic Fibrosis

Studies at this site

• A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease — Recruiting now
• A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) — Recruiting now
• Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) — Recruiting now
• Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer — Recruiting now
• DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02] — Completed
• Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF) — Completed
• DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03] — Running, not enrolling
• Trilaciclib (G1T28) in Patients With Previously Treated Extensive Stage SCLC Receiving Topotecan Chemotherapy — Completed
• Oral Omadacycline vs. Placebo in Adults With NTM Pulmonary Disease Caused by Mycobacterium Abscessus Complex (MABc) — Completed
• A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1) — Stopped early
• COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis — Completed
• Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency — Completed
• Clinical Effectiveness Of High Frequency Chest Wall Oscillation (HFCWO) In A Bronchiectasis Population — Completed
• Trial to Evaluate Efficacy and Safety of Lenabasum in Cystic Fibrosis — Completed
• AeroVanc in the Treatment of Methicillin-resistant Staphylococcus Aureus Infection in Patients With Cystic Fibrosis — Completed
• Using a Community-level Just-in-Time Adaptive Intervention to Address COVID-19 Testing Disparities — Status unconfirmed
• Study of Aztreonam for Inhalation in Children With Cystic Fibrosis and New Infection of the Airways by Pseudomonas Aeruginosa Bacteria — Stopped early
• Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype — Completed
• Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype — Stopped early
• Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency — Completed
• A Phase 3 Study of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF) — Completed
• Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung Disease — Completed
• Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium Complex — Completed
• Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM) — Completed
• Tigecycline for Treatment of Rapidly Growing Mycobacteria — Completed
• Azithromycin in the Treatment of M. Avium Complex Lung Disease — Completed
• Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung Disease — Completed
• Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency — Completed
• Equivalence Study of Specificity of PPD — Status unconfirmed
• Dose Study of Tuberculin Purified Protein Derivative (JHP/Dose) — Status unconfirmed
• IVIG - West Nile Encephalitis: Safety and Efficacy — Completed