The Methodist Hospital Research Institute

Houston, Texas 77030

9 studies enrolling now · 59 studies all time

What they study most

Acute Cartilage Injury, Acute Myeloid Leukemia, Adult Primary Hepatocellular Carcinoma, Advanced Solid Tumor and Lymphoma Malignancies, Alzheimer's Disease, Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Aortic Stenosis, Articular Cartilage Disorder, Atherosclerosis of Native Arteries of the Extremities, Atrial Fibrillation

Studies at this site

• Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread — Recruiting now
• A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart — Recruiting now
• AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions — Recruiting now
• Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission — Recruiting now
• Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord — Recruiting now
• A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE) — Recruiting now
• A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients — Completed
• A Study to Learn About the Safety of BIIB122 Tablets and Whether They Can Slow the Worsening of Early-Stage Parkinson's Disease in Adults Between the Ages of 30 and 80 — Completed
• Deep Learning-enhanced Personalized Monitoring of Aortic Stenosis - The DETECT-AS Prognostic Study — Enrolling by invitation
• Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301) — Running, not enrolling
• ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement — Running, not enrolling
• DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02] — Completed
• A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension — Enrolling by invitation
• Artificial Urinary Sphincter Clinical Outcomes — Completed
• Deep Learning Enhanced Detection of Aortic Stenosis - The DETECT-AS-Diagnostic Study — Enrolling by invitation
• Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04] — Running, not enrolling
• A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1) — Stopped early
• Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER — Stopped early
• Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST — Stopped early
• A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease — Stopped early
• Sorafenib Tosylate Following a Liver Transplant in Treating Patients With Liver Cancer — Completed
• ABSORB III Randomized Controlled Trial (RCT) — Completed
• An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD) — Completed
• A Study of HyQvia and Gammagard Liquid (Kiovig) in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) — Completed
• ELUVIA™ Drug-eluting Stent Versus Zilver® PTX® Stent — Completed
• A Study of TAK-659 in Adult Participants With Advanced Solid Tumor and Lymphoma Malignancies — Completed
• 221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease — Stopped early
• Safety and Efficacy Trial of RPC1063 for Moderate to Severe Ulcerative Colitis — Completed
• Pilot Study to Evaluate Safety & Biological Effects of Orally Administered Reparixin in Early Breast Cancer — Stopped early
• Phase 1 Dose Escalation, Single Dose Study to Assess Safety and Pharmacokinetics of BAX930 in Hereditary Thrombotic Thrombocytopenic Purpura (TTP) — Completed
• Use of Recombinant Adenovirus Therapy to Treat Localized Prostate Cancer — Completed
• Study of the Penumbra Coil 400 System to Treat Aneurysm — Completed
• Study to Evaluate the Safety and Tolerability of IV Doses of BMS-906024 in Subjects With Advanced or Metastatic Solid Tumors — Completed
• Efficacy and Safety Study of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn's Disease — Stopped early
• Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia — Stopped early
• Safety Study of ExAblate for the Treatment of Uterine Fibroids — Completed
• Irrigated Ablation System Evaluation for Atrial Fibrillation (AF) — Completed
• A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma — Completed
• KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures — Stopped early
• Neocartilage Implant to Treat Cartilage Lesions of the Knee — Stopped early
• Dose Range Study of Anamorelin in Patients With Non-small Cell Lung Cancer — Completed
• Rheos® Pivotal Trial — Completed
• aHUS Observational Long Term Follow-Up — Stopped early
• Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese — Stopped early
• Objective Assessment of Technical Skills in Cardiothoracic Surgery — Completed
• Clinical Study of the CardioFocus Endoscopic Ablation System - Adaptive Contact (EAS-AC) for the Treatment of Symptomatic Atrial Fibrillation — Completed
• Safety and Efficacy Study of GM-CSF, Thalidomide Plus Docetaxel in Prostate Cancer — Stopped early
• Phase I/II Trial of RAD001 Plus Nexavar in Patients With Kidney Cancer — Completed
• Activity of TroVax® Alone vs. TroVax® Plus GM-CSF in Patients With Prostate Cancer — Completed
• Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation — Completed