Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission
Recruiting now · Phase 2
Conditions studied: Acute Myeloid Leukemia, Leukemia
In brief
This clinical two-arm trial is designed to evaluate two doses of quizartinib as maintenance therapy after induction/consolidation in participants with FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) (+) acute myeloid leukemia (AML) in first complete remission (CR) who have not received allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Key facts
- Study ID
- NCT06824168
- Run by
- Daiichi Sankyo
- People needed
- 130
- Starts
- 2025-07-18
- Expected to finish
- 2032-07-14
- Last updated by the study team
- 2026-06-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Nanfang Hospital of Southern Medical University — Guangzhou, China (enrolling)
- The First Affiliated Hospital of Nanchang University — Nanchang, China (enrolling)
- Peking University Third Hospital — Beijing, China (enrolling)
- Guangdong Provincial People's Hospital — Guangzhou, China (enrolling)
- Sun Yat-sen University Cancer center — Guangzhou, China (enrolling)
- The First Affiliated Hosptial of Zhejiang University School of Medicine — Hangzhou, China (enrolling)
- The Methodist Hospital Research Institute — Houston, Texas, United States (enrolling)
- The University of Texas MD Anderson Cancer Center — Houston, Texas, United States (enrolling)
- The First Hospital of Jilin University — Changchun, China (enrolling)
- Austin Health — Australia, Australia (enrolling)
- St. Vincent's Hospital Melbourne — Darlinghurst, Australia (enrolling)
- The Alfred Hospital — Melbourne, Australia (enrolling)
- Spoknwrd Clinical Trials Inc. — Easton, Pennsylvania, United States (enrolling)
- Gold Coast University Hospital — Southport, Australia (enrolling)
- Westmead Hospital — Sydney, Australia (enrolling)
- Hospital Erasto Gaertner - Liga Paranaense de Combate ao Cancer — Curitiba, Brazil (enrolling)
- Cetus Hospital Dia Oncologia — Minas Gerai, Brazil (enrolling)
- Hospital de Clínicas de Porto Alegre — Porto Alegre, Brazil (enrolling)
- Irmandade da Santa Casa de Misericórdia de Porto Alegre Centro Multidisciplinar de Pesquisa — Porto Alegre, Brazil (enrolling)
- INCA - Instituto Nacional de Câncer — Rio de Janeiro, Brazil (enrolling)
- "Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto CIP - Centro Integrado de Pesquisa" — San Jose Rio Preto, Brazil (enrolling)
- Hospital Santa Marcelina — São Paulo, Brazil (enrolling)
- ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira — São Paulo, Brazil (enrolling)
- Peking Union Medical College Hospital — Beijing, China (enrolling)
- Zhong Da Hospital, Southeast University — Nanjing, China (enrolling)
Full record on ClinicalTrials.gov
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