The Hospital for Sick Children

Toronto, Ontario ON M5G 1X8

40 studies enrolling now · 224 studies all time

What they study most

ADA SCID, ALK Fusion-positive Solid or CNS Tumors, ALK-positive Histiocytosis, Abnormal Glucose Tolerance, Achondroplasia, Acute Graft vs Host Disease, Acute Kidney Injury, Acute Lymphocytic Leukemia in Relapse, Acute Myeloid Leukemia, Acute Myeloid Leukemia (AML), Acute Respiratory Distress Syndrome, Adenovirus

Studies at this site

• Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators — Recruiting now
• A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids) — Recruiting now
• A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors — Recruiting now
• Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa — Recruiting now
• Anesthetics and Analgesics in Children — Recruiting now
• A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants — Recruiting now
• A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD) — Recruiting now
• A Study of TYRA-300 in Children With Achondroplasia: BEACH301 — Recruiting now
• Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy — Recruiting now
• Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) — Recruiting now
• Primary Sclerosing Cholangitis in Children — Recruiting now
• Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP) — Recruiting now
• A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease — Recruiting now
• A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE) — Recruiting now
• A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A — Recruiting now
• A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome — Recruiting now
• Childhood Cancer Survivor Study — Recruiting now
• Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC — Recruiting now
• A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia — Recruiting now
• A Prospective Database of Infants With Cholestasis — Recruiting now
• Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma — Recruiting now
• Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection — Recruiting now
• ATrial Tachycardia PAcing Therapy in Congenital Heart — Recruiting now
• Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease — Recruiting now
• Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma — Recruiting now
• The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals — Recruiting now
• Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus — Recruiting now
• Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry — Recruiting now
• Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2 — Recruiting now
• Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others — Recruiting now
• Cord Clamping Among Neonates With Congenital Heart Disease — Recruiting now
• TrialNet Pathway to Prevention of T1D — Recruiting now
• International Rare Histiocytic Disorders Registry (IRHDR) — Recruiting now
• Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study — Recruiting now
• HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants — Recruiting now
• Optimizing Nutrition and Milk (Opti-NuM) Project — Recruiting now
• Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy — Recruiting now
• Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections — Recruiting now
• Simple Bone Cysts in Kids — Recruiting now
• Conditioning SCID Infants Diagnosed Early — Running, not enrolling
• Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study — Running, not enrolling
• Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis — Completed
• A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) — Running, not enrolling
• Research Study Investigating How Well NDec Works in People With Sickle Cell Disease — Completed
• Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy — Running, not enrolling
• AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD) — Running, not enrolling
• Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine — Running, not enrolling
• A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS) — Running, not enrolling
• Genetic Collection Protocol — Completed
• ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND) — Running, not enrolling