Birmingham Childrens Hospital

Birmingham B46NH

8 studies enrolling now · 74 studies all time

What they study most

ATP-Binding Cassette Subfamily C Member 6 Deficiency, Accelerated Phase Chronic Myelogenous Leukemia, Achondroplasia, Acute Graft-versus-host Disease, Acute Liver Failure, Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Adenovirus Infection, Arginase I Deficiency, Arthritis, Psoriatic, Atopic Dermatitis, Autosomal Recessive Hypophosphatemic Rickets

Studies at this site

• A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids) — Recruiting now
• A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE) — Recruiting now
• A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults — Recruiting now
• A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD) — Recruiting now
• A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight — Recruiting now
• A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis — Recruiting now
• Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD). — Recruiting now
• Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia — Recruiting now
• A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight — Running, not enrolling
• Natural History Study: ENPP1 Deficiency or the Early-Onset Form of ABCC6 Deficiency — Completed
• A Long-term Extension Study of Ustekinumab in Pediatric Participants — Running, not enrolling
• A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease — Completed
• Open-Label Extension Study to Assess GLM101 in PMM2-CDG Patients — Enrolling by invitation
• An Extension Study of Maralixibat in Patients With Progressive Familial Intrahepatic Cholestasis (PFIC) — Completed
• A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors — Running, not enrolling
• STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss — Running, not enrolling
• A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC) — Completed
• Prospective Clinical Assessment Study in Children With Achondroplasia (ACH) — Completed
• Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma — Stopped early
• A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Pregnant Women at High Risk for Early Onset Severe Hemolytic Disease of the Fetus and Newborn (HDFN) — Completed
• A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes — Completed
• Safety, Efficacy and Pharmacokinetics of NNC-0156-0000-0009 in Previously Treated Children With Haemophilia B. — Completed
• Safety and Efficacy of Nonacog Beta Pegol (N9-GP) in Previously Untreated Patients With Haemophilia B — Completed
• A Research Study on How Well Semaglutide Works in Adolescents With Overweight or Obesity — Completed
• MRX-800: A Long-Term Safety Study of Maralixibat in the Treatment of Cholestatic Liver Disease in Subjects Who Previously Participated in a Maralixibat Study — Completed
• A Research Study Looking at How Safe it is to Switch From Emicizumab to Mim8 in People With Haemophilia A (FRONTIER 5) — Completed
• Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects — Stopped early
• Study of Infigratinib in Children With Achondroplasia — Completed
• Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia — Running, not enrolling
• An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment — Completed
• International Registry of Congenital Portosystemic Shunt (IRCPSS) — Enrolling by invitation
• Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects — Completed
• Evaluation of Maralixibat in Biliary Atresia Response Post-Kasai — Completed
• A Study of ALS-008176 in Infants Hospitalized With RSV — Completed
• A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors — Stopped early
• Erlotinib Versus Oral Etoposide in Patients With Recurrent or Refractory Pediatric Ependymoma — Stopped early
• Arimoclomol Prospective Study in Participants Diagnosed With Niemann-Pick Disease Type C — Completed
• Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency — Completed
• Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH — Completed
• A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma — Completed
• A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD) — Completed
• A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation — Completed
• A Study of Potential Treatment-Responsive Biomarkers and Clinical Outcomes in Hunter Syndrome — Completed
• Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell Transplantation — Stopped early
• A Multicenter, Multinational, Observational Morquio A Registry Study (MARS) — Completed
• A Study to Evaluate the Efficacy and Safety of Maralixibat in Subjects With Progressive Familial Intrahepatic Cholestasis (MARCH-PFIC) — Completed
• Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma — Completed
• Open-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta — Stopped early
• Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients — Completed
• Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age — Completed