Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Baltimore, Maryland 21774

20 studies enrolling now · 483 studies all time

What they study most

AIDS Related Lymphoma, AIDS-Related Malignancy, AIDS-related Kaposi Sarcoma, Abnormal DNA Repair, Acupressure, Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia (ALL), Adult, Acute Lymphoblastic Lymphoma, Acute Myelogenous Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia (AML)

Studies at this site

• Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression — Recruiting now
• A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer — Recruiting now
• A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation — Recruiting now
• A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue — Recruiting now
• A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence — Recruiting now
• A Clinical Trial to Assess PVX7 Immunotherapy Regimens in Advanced Cervical Cancer Patients — Recruiting now
• 7-Days Water-Only Fasting or Ketone Supplementation Trial in Prostate Cancer — Recruiting now
• Cardiometabolic Screening Program — Recruiting now
• A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types — Recruiting now
• Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers — Recruiting now
• Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT) — Recruiting now
• Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia — Recruiting now
• The Safety and Tolerability of LBS-007 in Patients With Relapsed or Resistant Acute Leukaemias — Recruiting now
• Trial of Ixazomib for Kaposi Sarcoma — Recruiting now
• Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer — Recruiting now
• Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome — Recruiting now
• Study in Patients With Breast Cancer Leptomeningeal Metastasis — Recruiting now
• Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer — Recruiting now
• Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies — Recruiting now
• PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC — Recruiting now
• A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma — Running, not enrolling
• STEMVAC in Patients With Early Stage Triple Negative Breast Cancer — Running, not enrolling
• Monitoring Plasma Tumor DNA in Early-Stage Breast Cancer — Completed
• Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK) — Running, not enrolling
• A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma — Running, not enrolling
• A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance — Running, not enrolling
• Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer — Running, not enrolling
• Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM) — Running, not enrolling
• Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma — Stopped early
• Retroperitoneal Lymph Node Dissection in Treating Patients With Testicular Seminoma — Running, not enrolling
• Personalized Molecular Profiling in Cancer Treatment at Johns Hopkins — Running, not enrolling
• Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase Inhibitor — Running, not enrolling
• Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects — Running, not enrolling
• Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas — Running, not enrolling
• Johns Hopkins Breast Cancer Program Longitudinal Repository — Running, not enrolling
• Ivosidenib, Nivolumab, and Ipilimumab Combination in Previously Treated Subjects With Nonresectable or Metastatic IDH1 Mutant Cholangiocarcinoma — Stopped early
• Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion — Running, not enrolling
• Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma — Completed
• Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers — Running, not enrolling
• Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC — Completed
• A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation — Running, not enrolling
• A Study of Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma After Immune Checkpoint Inhibitor Treatment — Stopped early
• Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer — Running, not enrolling
• Study of DF1001 in Patients With Advanced Solid Tumors — Completed
• Expanded Access Study of TAS-120 in Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements — APPROVED_FOR_MARKETING
• Clinical Trial Assessing the Safety and Immunologic Correlates of Heterologous Prime-Boost With pNGVL4a-Sig/E7(Detox)/HSP70 and TA-HPV in Healthy Donors Followed by Peripheral Blood Collection — Enrolling by invitation
• Carboplatin and Nab-Paclitaxel With or Without Vorinostat in Treating Women With Newly Diagnosed Operable Breast Cancer — Running, not enrolling
• Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies — Completed
• SPARK-ALL: Calaspargase Pegol in Adults With ALL — Stopped early
• Safety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer — Completed