Duke university health system

Durham, North Carolina 27750

46 studies enrolling now · 212 studies all time

What they study most

Acquired Immunodeficiency Syndrome, Acute Coronary Syndromes, Acute HIV Infection, Acute Ischemic Stroke, Acute Leukemia, Acute Lung Injury, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia (AML), Adrenal Insufficiency, Adult Spinal Deformity, Advanced Cancer

Studies at this site

• OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events — Recruiting now
• A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome — Recruiting now
• Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy — Recruiting now
• Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network — Recruiting now
• CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis — Recruiting now
• Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease — Recruiting now
• Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) — Recruiting now
• A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED) — Recruiting now
• Risk Stratification in Children With Concussion — Recruiting now
• Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX) — Recruiting now
• Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity — Recruiting now
• Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers — Recruiting now
• A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome — Recruiting now
• Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion — Recruiting now
• A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM) — Recruiting now
• Study of Olutasidenib and Temozolomide in HGG — Recruiting now
• Targeted Pediatric High-Grade Glioma Therapy — Recruiting now
• Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs — Recruiting now
• IL-17 Blockade to Decrease irAEs (REPLAY) — Recruiting now
• HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM — Recruiting now
• Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers — Recruiting now
• Ultrasound Simulation Case-based Workshop Implementation and Impact Assessment — Recruiting now
• Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia — Recruiting now
• Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant — Recruiting now
• REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19 — Recruiting now
• A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease — Recruiting now
• Development & Validation of Preoperative Objective Physiological Evaluation — Recruiting now
• The WISER Study: Web Based Methods for Enhancing Resilience — Recruiting now
• A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion — Recruiting now
• The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial — Recruiting now
• Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia — Recruiting now
• Complex Adult Deformity Surgery (CADS) — Recruiting now
• Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients — Recruiting now
• Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0 — Recruiting now
• Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery — Recruiting now
• Duke Customized Aortic Aneurysm Repair With Endovascular Stent-grafts - Duke CARES Trial — Recruiting now
• HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT — Recruiting now
• Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery — Recruiting now
• Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans — Recruiting now
• Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer — Recruiting now
• Excision of Lymph Node Trial (EXCILYNT) (Mel69) — Recruiting now
• Ferritin and Iron Burden in SAH sIRB — Running, not enrolling
• A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS) — Running, not enrolling
• IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency — Starting soon
• Accelerating TMS for Cervical Dystonia — Enrolling by invitation
• 5-SENSE Score Validation Study — Enrolling by invitation
• Extending Preservation and Assessment Time of Donor Lungs Using the Toronto EVLP System™ at a Dedicated EVLP Facility — Completed
• Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke — Starting soon
• PATHFINDER 2: A Multi-Cancer Early Detection Study — Running, not enrolling
• Eat Well Produce Benefit for Diabetes and Food Insecurity — Completed