Aquatic Versus Land-Based Exercise in Women With Lipedema
Starting soon · Not applicable
Conditions studied: Lipedema
In brief
To evaluate optimal workout environments, a 12-week study assigned women with moderate-to-severe lipedema to three distinct protocols: supervised pool workouts, equivalent land-based training, or basic standard monitoring. Researchers tracked walking endurance alongside tissue composition, fluid levels, pain intensity, and general well-being. The trial posited that structured activity beats routine care alone, with water-based exercise potentially offering superior relief due to buoyancy and hydrostatic fluid compression.
Key facts
- Study ID
- NCT07756463
- Run by
- Cairo University
- People needed
- 60
- Starts
- 2026-08-27
- Expected to finish
- 2027-10-01
- Last updated by the study team
- 2026-08-10
Who can join
Age: 35 and older, up to 45. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Women diagnosed with lipedema for at least five years
- Had stage 2 or 3 and type 2 or 3 disease
- Had a body mass index of ≥25 and <40 kg/m²
- Able to walk independently, with or without their usual assistive device
- Had received medical clearance to participate in moderate-intensity aquatic and land-based exercise
- Able to understand the study procedures and provide written informed consent.
You may not qualify if…
- Had clinically significant lymphedema, uncontrolled chronic venous insufficiency, acute thrombosis, or another major cause of lower-limb edema
- Had open wounds, active skin infection, fever, or another infectious condition incompatible with pool use
- Had uncontrolled cardiovascular, metabolic, respiratory, or neurological disorder that could compromise exercise safety; a cardiac pacemaker or congestive heart failure; pregnancy; active cancer or ongoing chemotherapy, immunotherapy, or radiotherapy
- Had history of bariatric surgery, recent major surgery, or liposuction; current use of weight-loss medication
- Had current participation in structured aquatic or lower-limb exercise exceeding the protocol-defined threshold; or severe fear of water or inability to enter and exit the pool safely.
Full record on ClinicalTrials.gov
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