Early Versus Delayed Ileostomy Closure Following Bowel Surgery: A Randomized Controlled Trial

Completed · Not applicable

Conditions studied: Colorectal Diseases, Intestinal Diseases, Ileostomy

In brief

Temporary ileostomy is commonly created following bowel surgery to protect distal anastomoses and reduce the consequences of anastomotic leakage. However, the optimal timing for ileostomy closure remains controversial. Early closure may improve quality of life and reduce stoma-related complications, whereas delayed closure may allow better recovery but prolong stoma-related morbidity and hospital care. This randomized controlled trial aims to compare the mean post-operative hospital stay between early (within 8 weeks) and delayed (after 8 weeks) ileostomy closure following bowel surgery. Sixty eligible patients will be randomized equally into two groups. The findings will help determine the optimal timing of ileostomy reversal and may improve patient outcomes while reducing healthcare utilization.

Key facts

Study ID

NCT07754227

Run by

Dr. Waseem Ullah

People needed

73

Starts

2026-01-02

Expected to finish

2026-07-08

Last updated by the study team

2026-08-10

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-65 years. Male or female participants. Patients with a temporary ileostomy following bowel surgery. Patients scheduled for elective ileostomy closure. Participants willing to provide written informed consent.

You may not qualify if…

• Abdominal wall dehiscence. Tubercular perforation. Peritoneal contamination. Patients medically unfit for surgery. Refusal to provide informed consent.

Where it is running

• Lady Reading Hospital — Peshawar, Pakistan

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.