Effects of Adaptive Difficulty Computerized Cognitive Training on Cognitive Function Improvement in Older Adults With Mild Cognitive Impairment

Starting soon · Not applicable

Conditions studied: Cognitive Dysfunction, Cognitive Disorder, Cognitive Training

In brief

This study aims to evaluate the effectiveness of adaptive computerized cognitive training (CCT) in improving cognitive function among community-dwelling older adults with mild cognitive impairment (MCI) and to compare the maintenance effects of different training frequencies after the initial intervention. A quasi-experimental study will be conducted in three communities in Shenyang, Liaoning Province, China. All participants will receive a 12-week adaptive CCT program. Participants will be assigned to either a high-frequency maintenance training group or a training discontinuation group. Cognitive assessments will be performed at baseline, immediately after the intervention, and during follow-up. The primary outcome is global cognitive function, while secondary outcomes include memory, attention, executive function, language, visuospatial ability, and activities of daily living. The findings of this study are expected to provide evidence for optimizing computerized cognitive training programs and long-term management strategies for older adults with MCI in community settings.

Key facts

Study ID

NCT07753382

Run by

China Medical University, China

People needed

36

Starts

2026-08-10

Expected to finish

2027-01-10

Last updated by the study team

2026-08-07

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >= 60 years;
• Planning to reside in the community for at least 12 months, with no intention to move into a nursing home;
• No clinical diagnosis of dementia;
• Meeting the diagnostic criteria for mild cognitive impairment (MCI) as defined in the Chinese Expert Consensus on the Diagnosis and Treatment of Alzheimer's Disease-Related Mild Cognitive Impairment (2021), The cut-off scores for the Beijing version of the Montreal Cognitive Assessment (MoCA) were adjusted for educational level: <=13 for junior high school or below, <=19 for high school, and <=24 for college education or above. Mini-Mental State Examination (MMSE) score >= 24; Activities of Daily Living (ADL) score <23.
• Able to use a mobile application (mini program) to perform cognitive training.

You may not qualify if…

• Individuals unable to complete the questionnaires due to hearing or visual impairments;
• Those with other organic diseases of the central nervous system, such as brain tumors, epilepsy, or Parkinson's disease;
• Those diagnosed with severe mental disorders, such as schizophrenia, depression, or anxiety disorders.

Where it is running

• Ren'ai Changwan Community Elderly Care Service Station, Dadong — Shenyang, Liaoning, China

Full record on ClinicalTrials.gov

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