Aesthetic Masking and Resin Infiltration Time in MIH-affected Incisors

Starting soon · Not applicable

Conditions studied: Molar Incisor Hypomineralization

In brief

Background: Resin infiltration often shows unpredictable outcomes in teeth affected by molar incisor hypomineralisation (MIH) due to variable enamel porosities, hypermineralised surface layers, and elevated protein content. Different pretreatment modalities alongside modified resin infiltration protocols have been suggested to enhance aesthetic masking and the required resin infiltration time. Aim: To compare the effectiveness of transillumination-guided 5.25% NaOCl pretreatment following macroabrasion, with macroabrasion alone, each with 10-second hydrochloric acid (HCl) etching intervals, on aesthetic masking and resin infiltration time required in MIH-affected incisors.

Key facts

Study ID

NCT07753070

Run by

Alexandria University

People needed

100

Starts

2026-08-10

Expected to finish

2027-03-30

Last updated by the study team

2026-08-07

Who can join

Age: 8 and older, up to 13. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Healthy children with MIH-related mild white creamy opacities on permanent incisors, code 1 according to the European Academy of Paediatric Dentistry (EAPD) criteria.
• Clinically detectable isolated lesions (whether homogeneous or heterogeneous on the incisal and middle thirds of the buccal surface of the selected teeth.
• Patients with score 3 (positive) or score 4 (definitely positive) according to Frankl behavioral rating scale
• Parents or legal guardians accepting to sign a written consent and join the study

You may not qualify if…

• MIH-affected permanent incisors with post-eruptive enamel breakdown, cavitated lesions, restorations, or previously treated with surface layer removal or remineralising agents in the previous six months.
• Children with an allergy history

Where it is running

• Outpatient Clinic of Pediatric dentistry, Faculty of dentistry, Alexandria University, Egypt — Alexandria, Egypt

Full record on ClinicalTrials.gov

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