HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding

Starting soon

Conditions studied: Hemorrhage, Gastrointestinal Hemorrhage, Hemoptysis, Postpartum Hemorrhage

In brief

This observational study will collect information from adult patients in Japan who are treated with Histoacryl® to stop bleeding from arteries in the chest or abdomen, in order to better understand how well the treatment works and how safe it is during routine medical care.

Key facts

Study ID

NCT07753005

Run by

Aesculap AG

People needed

176

Starts

2026-09-30

Expected to finish

2028-06-01

Last updated by the study team

2026-08-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Active thoracoabdominal arterial bleeding diagnosed by endoscopy, catheter angiography, or computed tomography angiography (CTA).
• Planned embolization treatment using Histoacryl® as the sole embolic agent for the target lesion.
• No endoleak following thoracic endovascular aortic repair (TEVAR) or endovascular abdominal aortic repair (EVAR).
• Patients with malignant tumors must have an expected survival of at least 1 month.
• Written informed consent obtained from the patient or a legally authorized representative.

You may not qualify if…

• Previous embolization in the target vascular territory.
• Known allergy or hypersensitivity to n-butyl cyanoacrylate (NBCA), Lipiodol®, or related treatment components.
• Use of adjunctive embolic agents in the same target location.
• Planned surgical treatment after embolization as part of a predefined two-step treatment strategy.
• Severe septicemia.
• Participation in another clinical trial.
• Target vessels unsuitable for safe Histoacryl® injection.
• Empiric embolization without identification of a target bleeding location.
• Pregnancy, with the exception of patients treated for postpartum hemorrhage.

Where it is running

• Aichi Cancer Center Hospital — Nagoya, Aichi-ken, Japan
• Fujita Health University Hospital — Toyoake, Aichi-ken, Japan
• National Cancer Center Hospital East — Kashiwa, Chiba, Japan
• Gifu University Hospital — Gifu, Gifu, Japan
• Hokkaido University Hospital — Sapporo, Hokkaido, Japan
• Hyogo Medical University Hospital — Nishinomiya, Hyōgo, Japan
• St. Marianna University Hospital — Kawasaki, Kawasaki, Japan
• Nara Medical University Hospital — Kashihara, Nara, Japan
• Shizuoka Cancer Center — Nagaizumi-chō, Shizuoka, Japan
• National Cancer Center Hospital, — Tokyo, Tokyo, Japan
• Teikyo University Hospital — Tokyo, Tokyo, Japan

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.