High-Intensity Interval Resistance Training and Low-to-Moderate-Intensity Resistance Training in Upper Extremity Muscles

Completed · Not applicable

Conditions studied: Young Adults

In brief

High-intensity interval resistance training (HIIRT) has emerged as a time-efficient alternative to conventional resistance training; however, evidence regarding upper-extremity-focused HIIRT and its multidimensional effects remains limited. This randomized controlled trial aims to compare the effects of upper-extremity HIIRT and low-to-moderate-intensity resistance training (LMRT) on muscle strength, functional capacity, cognition, mental health, and health-related quality of life in healthy young adults. Forty-nine healthy young adults aged 18-25 years will be randomly allocated to one of three groups: HIIRT, LMRT, or a control group. Participants in the intervention groups will complete supervised upper-extremity resistance training sessions twice weekly for 8 weeks, while the control group will receive no structured exercise intervention. Outcome measures will include isotonic upper-extremity muscle strength, the Six-Minute Walk Test, the Montreal Cognitive Assessment, the State-Trait Anxiety Inventory, the Generalized Anxiety Disorder-7 questionnaire, the Dispositional Flow Scale-2, and the Short Form-36 Health Survey. The study is designed to evaluate the effects of the two resistance training protocols on physical, cognitive, and psychological outcomes in healthy young adults.

Key facts

Study ID

NCT07752901

Run by

Hacettepe University

People needed

49

Starts

2026-05-18

Expected to finish

2026-07-28

Last updated by the study team

2026-08-07

Who can join

Age: 18 and older, up to 25. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy young adults aged 18 to 25 years.
• Ability to understand the study procedures and provide written informed consent. Ability to participate safely in an upper-extremity resistance training program. Willingness to attend supervised exercise sessions twice weekly for 8 weeks.
• No participation in another clinical trial during the study period.

You may not qualify if…

• Presence of cardiovascular disease.
• Presence of neurological disease.
• Presence of psychiatric disorder.
• Presence of orthopedic disease or musculoskeletal condition limiting exercise participation.
• Presence of any systemic disease that may interfere with exercise training or study assessments.
• History of surgery affecting participation in the exercise program.
• Cognitive or psychological conditions that could interfere with completion of the assessments.
• Inability or unwillingness to comply with the study protocol.
• Refusal to provide written informed consent.

Where it is running

• Munzur University Faculty of Health Sciences — Tunceli, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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