Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis Remission
Recruiting now · Not applicable
Conditions studied: Ulcerative Colitis (Disorder), Inflammatory Bowel Disease (IBD)
In brief
This study will evaluate whether a 12-week dietary intervention can improve gut health, inflammation, and quality of life in adults with ulcerative colitis in remission. Participants will be randomly assigned to one of three groups: a Mediterranean diet, a Mediterranean diet combined with time-restricted feeding (eating within an 8-hour window each day), or standard dietary advice. The Mediterranean diet emphasizes fruits, vegetables, whole grains, legumes, nuts, olive oil, and fish, while limiting processed foods and red meat. The main outcome will be changes in short-chain fatty acids in stool samples, which are markers of gut health. Additional outcomes include changes in inflammation markers, gastrointestinal symptoms, and quality of life. The results of this study may help identify effective dietary strategies to support patients with ulcerative colitis.
Key facts
- Study ID
- NCT07752446
- Run by
- Pontificia Universidad Catolica de Chile
- People needed
- 45
- Starts
- 2026-04-10
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-08-07
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults aged 18 to 60 years
- Diagnosis of ulcerative colitis
- Clinical remission for at least 6 months
- Fecal calprotectin < 250 µg/g in the last 3 months
- Daily eating window ≥ 11 hours
You may not qualify if…
- Active ulcerative colitis
- History of gastrointestinal surgery
- Liver or kidney disease
- Pregnancy
- Eating disorders
- Use of supplements (protein, antioxidants, probiotics)
- Current restrictive diets (vegetarian, vegan, gluten-free, low-FODMAP)
- High levels of physical activity
Where it is running
- Pontificia Universidad Católica de Chile — Santiago, Santiago Metropolitan, Chile (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.