Quality of Life, Psychosocial Burden, and Structural-functional Status in Adults With Spinal Deformity.
Recruiting now · Not applicable
Conditions studied: ASD, Scoliosis Idiopathic Adolescent, Scoliosis Idiopathic Adolescent Treatment
In brief
This study examines which factors influence quality of life in adults with a spinal deformity. It looks at imaging findings together with pain, daily functioning, psychosocial factors, and frailty to support more person-centred care. A total of 320 adults will participate in three groups: conservative treatment, first corrective surgery, or reoperation. All care follows standard practice; no experimental treatments are added. Participants complete questionnaires, and routine FASD tests and existing EOS/X-ray images may be used. Follow-up lasts up to 2 years, with scheduled assessments depending on whether treatment is surgical or conservative.
Key facts
- Study ID
- NCT07749534
- Run by
- Universitaire Ziekenhuizen KU Leuven
- People needed
- 320
- Starts
- 2026-08-01
- Expected to finish
- 2029-07-01
- Last updated by the study team
- 2026-08-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures
- Age at inclusion 18 years or older.
- Diagnosed with Adult spinal deformity
- Planned routine management through one of the following pathways:
- Conservative/non-operative management;
- Primary ASD surgery;
- Revision ASD surgery.
- Ability to complete the Dutch-language questionnaire package.
You may not qualify if…
- No valid informed consent.
- Missing baseline structural imaging required for endpoint determination. We allow images to be older than 2 years if no new radiographs are obtained, in accordance with the ALARA principle.
- Inability to complete the Dutch-language questionnaire package.
- Known cognitive impairment, severe psychiatric condition, or other condition that, in the Investigator's judgement, precludes valid informed consent or reliable completion of study assessments.
- Primary spinal condition other than adult spinal deformity that is expected to invalidate endpoint assessment, including acute traumatic, infectious, tumour-related, or inflammatory spinal pathology as the main reason for presentation.
Where it is running
- UZ Leuven — Leuven, Belgium (enrolling)
Full record on ClinicalTrials.gov
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