Evaluating the Intraoperative Analgesic Effect of Ultrasound Guided Erector Spinae Plane Block in Parturient Undergoing Elective Cesarean Section for Placenta Accreta Under General Anesthesia.
Completed · Not applicable
Conditions studied: Placenta Accreta, ESPB, C-section, General Anesthesia
In brief
Due to the significant risk of massive bleeding complicated by profound hypotension and coagulopathy and a high likelihood of hysterectomy during caesarean delivery, general anesthesia is generally regarded as the anesthetic of choice for patients with placenta accreta. The advantage of a planned general anesthetic is the ability to secure the airway in a controlled setting, before the onset of hemodynamic instability, airway edema or coagulopathy. A multidisciplinary approach may improve patient outcomes. However, it is necessary to maintain a good depth of anesthesia and sufficient analgesia and to consider the impact of anesthesia drugs on the fetus. Since all opioids, particularly those with high lipid solubility (e.g., remifentanil, fentanyl, and sufentanil), readily pass through the placenta to the fetus. Consequently, opioid administration is usually avoided until after delivery to reduce the risk of neonatal depression. The latest publications have reported that the erector spinae plane block is one of the components of multimodal analgesia techniques for pain management after different surgical procedures, including cesarean delivery.
Key facts
- Study ID
- NCT07748741
- Run by
- Kasr El Aini Hospital
- People needed
- 70
- Starts
- 2025-01-25
- Expected to finish
- 2025-12-30
- Last updated by the study team
- 2026-08-06
Who can join
Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- American Society of Anesthesiologists physical status II.
- Female patients aged 18 to 40 years' old.
- BMI less than 40.
- Diagnosed placenta accreta
You may not qualify if…
- • Patient's unwillingness to participate in the study.
- Contraindication to receive regional anesthesia.
- Patients with anticipated difficult airway.
- Allergy to any of the drugs used in the study
- Any apparent deformity in the spine.
- Hemodynamic instability.
- Fetal distress.
- Surgically complicated cases.
Where it is running
- Kasr Al Aini Hospitals — Cairo, Egypt
Full record on ClinicalTrials.gov
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