Outcome of Partial Pulpotomy in Permanent Mandibular Molars With Symptomatic Irreversible Pulpitis After Wound Lavage With Calcium Hypochlorite or Sodium Hypochlorite
Recruiting now · Not applicable
Conditions studied: Symptomatic Irreversible Pulpitis (SIP), Extremely Deep Caries
In brief
The aim of this randomised control trial is to compare the effect of wound lavage using 2.5% Ca(OCl)₂ and 2.5% NaOCl on the outcome of partial pulpotomy in mature permanent mandibular molars with symptomatic irreversible pulpitis (SIP).Primary objective is to evaluate and compare clinical and radiographic outcome of partial pulpotomy following use of 2.5% Ca(OCl)₂ and 2.5% NaOCl in mature permanent mandibular molars with symptomatic irreversible pulpitis.secondary objective is to evaluate OHRQoL and pain experience after use of 2.5% Ca(OCl)₂ and 2.5% NaOCl during partial pulpotomy in permanent mandibular molars with clinical signs indicative of symptomatic irreversible pulpitis.
Key facts
- Study ID
- NCT07748676
- Run by
- Postgraduate Institute of Dental Sciences Rohtak
- People needed
- 106
- Starts
- 2026-04-29
- Expected to finish
- 2027-10-28
- Last updated by the study team
- 2026-08-06
Who can join
Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- patients aged 18-40 years
- Mature permanent mandibular molars with extremely deep caries (caries penetrating the entire thickness of the dentine radiographically, without radiopaque zone separating lesion from the pulp) and clinical diagnosis of SIP with PAI score ≤ 2
- Periodontally healthy teeth (probing pocket depth ≤3 mm and mobility within normal limit)
- Patients having physical status of class 1 or 2 according to ASA classification
- Pulpal bleeding could be controlled within 10 min following pulp amputation
You may not qualify if…
- Non restorable teeth
- No pulp exposure even after complete caries excavation
- Necrotic or partially necrotic pulp upon exposure
- Presence of sinus tract or soft tissue swelling
- Radiographic signs of internal or external root resorption
- Pregnant women
Where it is running
- PGIDS — Rohtak, Haryana, India (enrolling)
Full record on ClinicalTrials.gov
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