Comparison of Gingival Depigmentation Using Microneedling and Microneedling With Glutathione Gel - A Split Mouth Clinical Trial

Completed · Not applicable

Conditions studied: Gingiival Hyperpigmentation

In brief

The colour of gingiva is important determinant of smile esthetics.Owing to increasing awareness and demand for cosmetic procedures over the past decade, gingival depigmentation has gained popularity among periodontal plastic surgical procedures.

Key facts

Study ID

NCT07748507

Run by

Krishnadevaraya College of Dental Sciences & Hospital

People needed

15

Starts

2025-06-25

Expected to finish

2026-07-28

Last updated by the study team

2026-08-05

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients between the age group of 18 to 45 years
• Systemically healthy subjects
• Maxillary or mandibular keratinised gingiva with minimum mean SEMPI score of 1(light grey / brown pigmentation) and above.

You may not qualify if…

• Patients with thin gingival phenotype(<1mm)
• Patients on drugs that cause oral pigmentation like antimalarials,minocycline, oral contraceptives etc.,
• Systemic disorders that cause oral pigmentation ,Pregnant and lactating women
• Subjects with history of smoking.

Where it is running

• krishnadevaraya college of dental sciences and Hospital — Bangalore, Kranataka, India

Full record on ClinicalTrials.gov

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