Pain and Anxiety During Vital Pulp Therapy Using Different Local Anesthesia Techniques in Children

Starting soon

Conditions studied: Pediatric, Anesthesia

In brief

This prospective observational study aims to evaluate the effects of different local anesthesia techniques on dental anxiety and pain in children undergoing vital pulp therapy of permanent mandibular first molars. Conventional inferior alveolar nerve block and two computer-controlled local anesthetic delivery (CCLAD) systems used in routine clinical practice will be compared. The choice of anesthesia technique will be based on the clinician's routine decision-making, and no additional intervention or modification of standard treatment will be performed for research purposes. Dental anxiety, pain, physiological parameters, and postoperative complications will be assessed using validated clinical scales and routine clinical measurements. The findings may help improve pain and anxiety management during pediatric dental treatment while supporting evidence-based selection of local anesthesia techniques.

Key facts

Study ID

NCT07748390

Run by

Recep Tayyip Erdogan University Training and Research Hospital

People needed

120

Starts

2026-08-01

Expected to finish

2026-12-30

Last updated by the study team

2026-08-05

Who can join

Age: 8 and older, up to 10. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Children aged 8-10 years.
• Children and parents/legal guardians who agree to participate in the study and provide informed consent.
• Patients requiring vital pulp therapy of a permanent mandibular first molar.
• Patients classified as Frankl Behavior Rating Scale score 3 or 4. Systemically healthy children (ASA I).
• Children with adequate cognitive and communication abilities to understand the study procedures and pain/anxiety assessment scales.
• Permanent mandibular first molars without clinical or radiographic signs of abscess, fistula, or periapical pathology.

You may not qualify if…

• Children with systemic diseases or medical conditions affecting dental treatment.
• Children classified as Frankl Behavior Rating Scale score 1 or 2.
• Patients with known allergy or hypersensitivity to local anesthetic agents (e.g., lidocaine, articaine).
• Teeth with acute dental infection signs, including abscess, cellulitis, or extensive infection.
• Teeth showing clinical or radiographic evidence of periapical pathology.
• Children unable to understand or complete pain and anxiety assessment scales due to cognitive, visual, hearing, or communication limitations.
• Patients who do not comply with the study procedures or withdraw consent.

Full record on ClinicalTrials.gov

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