Acupuncture to Prevent Nausea and Vomiting After Stem Cell Transplant
Enrolling by invitation · Not applicable · Has a placebo group
Conditions studied: Chemotherapy-Induced Nausea and Vomiting (CINV), Hematopoietic Stem Cell Transplantation (HSCT)
In brief
This study is testing whether acupuncture at a point on the wrist called "Neiguan" can help reduce nausea and vomiting in patients undergoing stem cell transplantation. Participants will receive either real acupuncture or standard care. We hope to find a safe way to improve comfort during cancer treatment.
Key facts
- Study ID
- NCT07747194
- Run by
- Xiao Wang
- People needed
- 80
- Starts
- 2026-07-01
- Expected to finish
- 2027-12-30
- Last updated by the study team
- 2026-08-05
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18-65 years, either sex. Patients scheduled to receive a conditioning (preparative) regimen for hematopoietic stem cell transplantation (HSCT).
- Life expectancy ≥ 3 months. Eastern Cooperative Oncology Group (ECOG) performance status of 0-2. Women of childbearing potential must have a negative pregnancy test (serum or urine) within 7 days prior to enrollment.
- Voluntary participation with signed informed consent.
You may not qualify if…
- Received chemotherapy with highly emetogenic agents within 14 days prior to enrollment.
- Received radiotherapy within 7 days prior to enrollment, or planned radiotherapy during the study period.
- Known hypersensitivity to any study drug or its excipients. Complicated with gastrointestinal obstruction, brain metastasis with symptoms of increased intracranial pressure, or any other condition that may cause and/or exacerbate nausea and vomiting.
- Active infection. Unable to take oral medications. Use of any anti-emetic medication (including corticosteroids) within 48 hours or 5 half-lives of the drug (whichever is longer) prior to enrollment.
- Any episode of nausea, vomiting, or retching within 24 hours prior to the first administration.
- Severe psychiatric illness or cognitive impairment that precludes understanding, reading, and completing patient diaries.
- Any other condition that the investigator deems would make the patient unsuitable for participation in this study.
Where it is running
- The General Hospital of Western Theater Command — Chengdu, Sichuan, China
Full record on ClinicalTrials.gov
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