Treatment Based on High Precision Cardiac Mapping
Starting soon · Phase 4
Conditions studied: VT Ablation, Arrhythmic Burden, Implantable Cardioverter-Defibrillator (ICD) Therapies, Slow-conduction Substrate
In brief
APOLO-VT aims to evaluate the feasibility, safety, and clinical impact of an integrated multimodal mapping workflow combining non-invasive structural and functional substrate characterization using Volumetric Electrocardiographic Imaging (ECGi) with invasive Electroanatomical Mapping (EAM) to support Ventricular tachycardia (VT) ablation targeting and verification.
Key facts
- Study ID
- NCT07746336
- Run by
- Hospital Clinic of Barcelona
- People needed
- 60
- Starts
- 2026-07-15
- Expected to finish
- 2028-07-01
- Last updated by the study team
- 2026-08-05
Who can join
Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18 years.
- Diagnosis of structural heart disease (ischemic or non-ischemic cardiomyopathy).
- Documented sustained monomorphic VT (clinical or inducible), or recurrent ICD therapies for VT.
- Scheduled for catheter ablation of VT according to current international guidelines.
- Ability to provide written informed consent.
- Ability to remain upright or seated to allow a video for 3D torso reconstruction for ECGi acquisition.
You may not qualify if…
- Age <18 years.
- Pregnant or breastfeeding women.
- Inability to provide informed consent due to physical or mental condition.
- Contraindication to computed tomography or cardiac magnetic resonance (magnetic resonance imaging-incompatible devices, claustrophobia).
- Contraindication to contrast agents (gadolinium allergy or severe renal dysfunction with estimated glomerular filtration rate <30 mL/min/1.73 m²).
- Inability to remain upright for torso 3D reconstruction required for ECGi.
- Life expectancy <1 year due to non-cardiac comorbidity.
Where it is running
- Hospital Clinic, University of Barcelona — Barcelona, Spain
Full record on ClinicalTrials.gov
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