Pupillary Dilation Reflex in Healthy Volunteers

Recruiting now

Conditions studied: Healthy Participants

In brief

This a single site, observational study that will examine how the pupil responds to neurostimulation under different conditions in healthy adults. The objective is to measure pupillary dilation reflex (PRD) in response to increasing neurostimulation intensities using the AlgometRx device.

Key facts

Study ID

NCT07746167

Run by

Children's National Research Institute

People needed

60

Starts

2026-04-29

Expected to finish

2027-06-01

Last updated by the study team

2026-08-04

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18-60 years.
• In good general health (self-reported).
• Able and willing to provide written informed consent.

You may not qualify if…

• Eye pathology that prevents accurate pupillometry.
• Pregnancy (Self-Report)
• Diagnosis of autoimmune disorders.
• Diagnosis of any neuropathic disorder
• Inability to complete questionnaires.

Where it is running

• Children's National Hospital — Washington D.C., District of Columbia, United States (enrolling)

Full record on ClinicalTrials.gov

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